Clinical Manifestations of an Outbreak of Monkeypox Virus in Captive Chimpanzees in Cameroon, 2016
© The Author(s) 2024. Published by Oxford University Press on behalf of Infectious Diseases Society of America. All rights reserved. For permissions, please e-mail: journals.permissionsoup.com..
Monkeypox virus (MPXV) is a reemerging virus of global concern. An outbreak of clade I MPXV affected 20 captive chimpanzees in Cameroon in 2016. We describe the epidemiology, virology, phylogenetics, and clinical progression of this outbreak. Clinical signs included exanthema, facial swelling, perilaryngeal swelling, and eschar. Mpox can be lethal in captive chimpanzees, with death likely resulting from respiratory complications. We advise avoiding anesthesia in animals with respiratory signs to reduce the likelihood of death. This outbreak presented a risk to animal care staff. There is a need for increased awareness and a One Health approach to preparation for outbreaks in wildlife rescue centers in primate range states where MPXV occurs. Control measures should include quarantining affected animals, limiting human contacts, surveillance of humans and animals, use of personal protective equipment, and regular decontamination of enclosures.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:229 |
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| Enthalten in: |
The Journal of infectious diseases - 229(2024), Supplement_2 vom: 26. März, Seite S275-S284 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Brien, Stephanie C [VerfasserIn] |
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| Anmerkungen: |
Date Completed 28.03.2024 Date Revised 28.03.2024 published: Print Citation Status MEDLINE |
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| doi: |
10.1093/infdis/jiad601 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| 520 | |a © The Author(s) 2024. Published by Oxford University Press on behalf of Infectious Diseases Society of America. All rights reserved. For permissions, please e-mail: journals.permissionsoup.com. | ||
| 520 | |a Monkeypox virus (MPXV) is a reemerging virus of global concern. An outbreak of clade I MPXV affected 20 captive chimpanzees in Cameroon in 2016. We describe the epidemiology, virology, phylogenetics, and clinical progression of this outbreak. Clinical signs included exanthema, facial swelling, perilaryngeal swelling, and eschar. Mpox can be lethal in captive chimpanzees, with death likely resulting from respiratory complications. We advise avoiding anesthesia in animals with respiratory signs to reduce the likelihood of death. This outbreak presented a risk to animal care staff. There is a need for increased awareness and a One Health approach to preparation for outbreaks in wildlife rescue centers in primate range states where MPXV occurs. Control measures should include quarantining affected animals, limiting human contacts, surveillance of humans and animals, use of personal protective equipment, and regular decontamination of enclosures | ||
| 650 | 4 | |a Journal Article | |
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| 650 | 4 | |a epidemiology | |
| 650 | 4 | |a mpox | |
| 650 | 4 | |a outbreak | |
| 650 | 4 | |a zoonosis | |
| 700 | 1 | |a LeBreton, Matthew |e verfasserin |4 aut | |
| 700 | 1 | |a Doty, Jeffrey B |e verfasserin |4 aut | |
| 700 | 1 | |a Mauldin, Matthew R |e verfasserin |4 aut | |
| 700 | 1 | |a Morgan, Clint N |e verfasserin |4 aut | |
| 700 | 1 | |a Pieracci, Emily G |e verfasserin |4 aut | |
| 700 | 1 | |a Ritter, Jana M |e verfasserin |4 aut | |
| 700 | 1 | |a Matheny, Audrey |e verfasserin |4 aut | |
| 700 | 1 | |a Tafon, Bibila G |e verfasserin |4 aut | |
| 700 | 1 | |a Tamoufe, Ubald |e verfasserin |4 aut | |
| 700 | 1 | |a Missoup, Alain D |e verfasserin |4 aut | |
| 700 | 1 | |a Nwobegahay, Julius |e verfasserin |4 aut | |
| 700 | 1 | |a Takuo, Jean Michel |e verfasserin |4 aut | |
| 700 | 1 | |a Nkom, Felix |e verfasserin |4 aut | |
| 700 | 1 | |a Mouiche, Moctar M M |e verfasserin |4 aut | |
| 700 | 1 | |a Feussom, Jean Marc K |e verfasserin |4 aut | |
| 700 | 1 | |a Wilkins, Kimberly |e verfasserin |4 aut | |
| 700 | 1 | |a Wade, Abel |e verfasserin |4 aut | |
| 700 | 1 | |a McCollum, Andrea M |e verfasserin |4 aut | |
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