The effect of mitochondrial recombination on fertilization success in blue mussels
Copyright © 2023 The Authors. Published by Elsevier B.V. All rights reserved..
The presence of doubly uniparental inheritance (DUI) in bivalves represents a unique mode of mitochondrial transmission, whereby paternal (male-transmitted M-type) and maternal (female-transmitted F-type) haplotypes are transmitted to offspring separately. Male embryos retain both haplotypes, but the M-type is selectively removed from females. Due to the presence of heteroplasmy in males, mtDNA can recombine resulting in a 'masculinized' haplotype referred to as Mf-type. While mtDNA recombination is usually rare, it has been recorded in multiple mussel species across the Northern Hemisphere. Given that mitochondria are the powerhouse of the cell, different mtDNA haplotypes may have different selective advantages under diverse environmental conditions. This may be particularly important for sperm fitness and fertilization success. In this study we aimed to i) determine the presence, prevalence of the Mf-type in Australian blue mussels (Mytilus sp.) and ii) investigate the effect of Mf-mtDNA on sperm performance (a fitness correlate). We found a high prevalence of recombined mtDNA (≈35 %) located within the control region of the mitochondrial genome, which occurred only in specimens that contained Southern Hemisphere mtDNA. The presence of two female mitotypes were identified in the studied mussels, one likely originating from the Northern Hemisphere, and the other either representing the endemic M. planulatus species or introduced genotypes from the Southern Hemisphere. Despite having recombination events present in a third of the studied population, analysis of sperm performance indicated no difference in fertilization success related to mitotype.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:913 |
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| Enthalten in: |
The Science of the total environment - 913(2024) vom: 25. Jan., Seite 169491 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Bramwell, Georgina [VerfasserIn] |
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| Links: |
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| Themen: |
DNA, Mitochondrial |
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| Anmerkungen: |
Date Completed 18.01.2024 Date Revised 18.01.2024 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.scitotenv.2023.169491 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
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| 245 | 1 | 4 | |a The effect of mitochondrial recombination on fertilization success in blue mussels |
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| 520 | |a Copyright © 2023 The Authors. Published by Elsevier B.V. All rights reserved. | ||
| 520 | |a The presence of doubly uniparental inheritance (DUI) in bivalves represents a unique mode of mitochondrial transmission, whereby paternal (male-transmitted M-type) and maternal (female-transmitted F-type) haplotypes are transmitted to offspring separately. Male embryos retain both haplotypes, but the M-type is selectively removed from females. Due to the presence of heteroplasmy in males, mtDNA can recombine resulting in a 'masculinized' haplotype referred to as Mf-type. While mtDNA recombination is usually rare, it has been recorded in multiple mussel species across the Northern Hemisphere. Given that mitochondria are the powerhouse of the cell, different mtDNA haplotypes may have different selective advantages under diverse environmental conditions. This may be particularly important for sperm fitness and fertilization success. In this study we aimed to i) determine the presence, prevalence of the Mf-type in Australian blue mussels (Mytilus sp.) and ii) investigate the effect of Mf-mtDNA on sperm performance (a fitness correlate). We found a high prevalence of recombined mtDNA (≈35 %) located within the control region of the mitochondrial genome, which occurred only in specimens that contained Southern Hemisphere mtDNA. The presence of two female mitotypes were identified in the studied mussels, one likely originating from the Northern Hemisphere, and the other either representing the endemic M. planulatus species or introduced genotypes from the Southern Hemisphere. Despite having recombination events present in a third of the studied population, analysis of sperm performance indicated no difference in fertilization success related to mitotype | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Mitochondrial masculinization | |
| 650 | 4 | |a Mytilus galloprovincialis | |
| 650 | 4 | |a Sex-reversal | |
| 650 | 4 | |a Whole mitochondrial genome | |
| 650 | 7 | |a DNA, Mitochondrial |2 NLM | |
| 700 | 1 | |a Schultz, Aaron G |e verfasserin |4 aut | |
| 700 | 1 | |a Jennings, Geordie |e verfasserin |4 aut | |
| 700 | 1 | |a Nini, Urmi Nishat |e verfasserin |4 aut | |
| 700 | 1 | |a Vanbeek, Caitlin |e verfasserin |4 aut | |
| 700 | 1 | |a Biro, Peter A |e verfasserin |4 aut | |
| 700 | 1 | |a Beckmann, Christa |e verfasserin |4 aut | |
| 700 | 1 | |a Dujon, Antoine M |e verfasserin |4 aut | |
| 700 | 1 | |a Thomas, Frédéric |e verfasserin |4 aut | |
| 700 | 1 | |a Sherman, Craig D H |e verfasserin |4 aut | |
| 700 | 1 | |a Ujvari, Beata |e verfasserin |4 aut | |
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