Tiny swabs : nasal swabs integrated into tube caps facilitate large-scale self-collected SARS-CoV-2 testing
The COVID-19 pandemic spurred the development of innovative solutions for specimen collection and molecular detection for large-scale community testing. Among these developments is the RHINOstic nasal swab, a plastic anterior nares swab built into the cap of a standard matrix tube that facilitates automated processing of up to 96 specimens at a time. In a study of unsupervised self-collection utilizing these swabs, we demonstrate comparable analytic performance and shipping stability compared to traditional anterior nares swabs, as well as significant improvements in laboratory processing efficiency. The use of these swabs may allow laboratories to accommodate large numbers of sample collections during periods of high testing demand. Automation-friendly nasal swabs are an important tool for high-throughput processing of samples that may be adopted in response to future respiratory viral pandemics.
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2024 |
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Erschienen: |
2024 |
Enthalten in: |
Zur Gesamtaufnahme - volume:62 |
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Enthalten in: |
Journal of clinical microbiology - 62(2024), 2 vom: 14. Feb., Seite e0128523 |
Sprache: |
Englisch |
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Beteiligte Personen: |
Pfau, Brian [VerfasserIn] |
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Links: |
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Themen: |
Journal Article |
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Anmerkungen: |
Date Completed 15.02.2024 Date Revised 04.03.2024 published: Print-Electronic Citation Status MEDLINE |
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doi: |
10.1128/jcm.01285-23 |
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funding: |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM366223518 |
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245 | 1 | 0 | |a Tiny swabs |b nasal swabs integrated into tube caps facilitate large-scale self-collected SARS-CoV-2 testing |
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520 | |a The COVID-19 pandemic spurred the development of innovative solutions for specimen collection and molecular detection for large-scale community testing. Among these developments is the RHINOstic nasal swab, a plastic anterior nares swab built into the cap of a standard matrix tube that facilitates automated processing of up to 96 specimens at a time. In a study of unsupervised self-collection utilizing these swabs, we demonstrate comparable analytic performance and shipping stability compared to traditional anterior nares swabs, as well as significant improvements in laboratory processing efficiency. The use of these swabs may allow laboratories to accommodate large numbers of sample collections during periods of high testing demand. Automation-friendly nasal swabs are an important tool for high-throughput processing of samples that may be adopted in response to future respiratory viral pandemics | ||
650 | 4 | |a Journal Article | |
650 | 4 | |a Research Support, Non-U.S. Gov't | |
650 | 4 | |a respiratory pathogens | |
650 | 4 | |a scaled testing | |
650 | 4 | |a specimen collection | |
700 | 1 | |a Opsahl, Jordan |e verfasserin |4 aut | |
700 | 1 | |a Crew, Ruben |e verfasserin |4 aut | |
700 | 1 | |a Best, Sabrina |e verfasserin |4 aut | |
700 | 1 | |a Han, Peter D |e verfasserin |4 aut | |
700 | 1 | |a Heidl, Sarah |e verfasserin |4 aut | |
700 | 1 | |a McDermot, Evan |e verfasserin |4 aut | |
700 | 1 | |a Stone, Jeremy |e verfasserin |4 aut | |
700 | 1 | |a Schwabe-Fry, Kristen |e verfasserin |4 aut | |
700 | 1 | |a MacMillan, Melissa P |e verfasserin |4 aut | |
700 | 1 | |a O'Hanlon, Jessica |e verfasserin |4 aut | |
700 | 1 | |a Sohlberg, Sarah |e verfasserin |4 aut | |
700 | 1 | |a Acker, Zack |e verfasserin |4 aut | |
700 | 1 | |a Ehmen, Brenna |e verfasserin |4 aut | |
700 | 1 | |a Englund, Janet A |e verfasserin |4 aut | |
700 | 1 | |a Konnick, Eric Q |e verfasserin |4 aut | |
700 | 1 | |a Chu, Helen Y |e verfasserin |4 aut | |
700 | 1 | |a Weil, Ana A |e verfasserin |4 aut | |
700 | 1 | |a Lockwood, Christina M |e verfasserin |4 aut | |
700 | 1 | |a Starita, Lea M |e verfasserin |4 aut | |
700 | 0 | |a Seattle Flu Alliance Investigators |e verfasserin |4 aut | |
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700 | 1 | |a Englund, Janet A |e investigator |4 oth | |
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700 | 1 | |a Shendure, Jay |e investigator |4 oth | |
700 | 1 | |a Starita, Lea M |e investigator |4 oth | |
700 | 1 | |a Waghmere, Alpana |e investigator |4 oth | |
700 | 1 | |a Weil, Ana A |e investigator |4 oth | |
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