Tiny swabs : nasal swabs integrated into tube caps facilitate large-scale self-collected SARS-CoV-2 testing

The COVID-19 pandemic spurred the development of innovative solutions for specimen collection and molecular detection for large-scale community testing. Among these developments is the RHINOstic nasal swab, a plastic anterior nares swab built into the cap of a standard matrix tube that facilitates automated processing of up to 96 specimens at a time. In a study of unsupervised self-collection utilizing these swabs, we demonstrate comparable analytic performance and shipping stability compared to traditional anterior nares swabs, as well as significant improvements in laboratory processing efficiency. The use of these swabs may allow laboratories to accommodate large numbers of sample collections during periods of high testing demand. Automation-friendly nasal swabs are an important tool for high-throughput processing of samples that may be adopted in response to future respiratory viral pandemics.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:62

Enthalten in:

Journal of clinical microbiology - 62(2024), 2 vom: 14. Feb., Seite e0128523

Sprache:

Englisch

Beteiligte Personen:

Pfau, Brian [VerfasserIn]
Opsahl, Jordan [VerfasserIn]
Crew, Ruben [VerfasserIn]
Best, Sabrina [VerfasserIn]
Han, Peter D [VerfasserIn]
Heidl, Sarah [VerfasserIn]
McDermot, Evan [VerfasserIn]
Stone, Jeremy [VerfasserIn]
Schwabe-Fry, Kristen [VerfasserIn]
MacMillan, Melissa P [VerfasserIn]
O'Hanlon, Jessica [VerfasserIn]
Sohlberg, Sarah [VerfasserIn]
Acker, Zack [VerfasserIn]
Ehmen, Brenna [VerfasserIn]
Englund, Janet A [VerfasserIn]
Konnick, Eric Q [VerfasserIn]
Chu, Helen Y [VerfasserIn]
Weil, Ana A [VerfasserIn]
Lockwood, Christina M [VerfasserIn]
Starita, Lea M [VerfasserIn]
Seattle Flu Alliance Investigators [VerfasserIn]
Bedford, Trevor [Sonstige Person]
Boeckh, Michael [Sonstige Person]
Chu, Helen Y [Sonstige Person]
Englund, Janet A [Sonstige Person]
Lockwood, Christina M [Sonstige Person]
Lutz, Barry R [Sonstige Person]
Prentice, Robin [Sonstige Person]
Shendure, Jay [Sonstige Person]
Starita, Lea M [Sonstige Person]
Waghmere, Alpana [Sonstige Person]
Weil, Ana A [Sonstige Person]

Links:

Volltext

Themen:

Journal Article
Research Support, Non-U.S. Gov't
Respiratory pathogens
Scaled testing
Specimen collection

Anmerkungen:

Date Completed 15.02.2024

Date Revised 04.03.2024

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1128/jcm.01285-23

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM366223518