Addressing the rising trend of high-risk pulmonary embolism mortality : Clinical and research priorities

© 2023 Society for Academic Emergency Medicine..

BACKGROUND: Deaths from high-risk pulmonary embolism (PE) appear to have increased in the US over the last decade. Modifiable risks contributing to this worrisome trend present opportunities for physicians, researchers, and healthcare policymakers to improve care.

METHODS: We sought to contextualize contemporary, high-risk PE epidemiology and examine clinical trials, quality improvement opportunities, and healthcare policy initiatives directed at reducing mortality.

RESULTS: We observed significant and modifiable excess mortality due to high-risk PE. We identified several opportunities to improve care including: (1) rapid translation of forthcoming data on reperfusion strategies into clinical practice; (2) improved risk stratification tools; (3) quality improvement initiatives to address presumptive anticoagulation practice gaps; and (3) adoption of health policy initiatives to establish pulmonary embolism response teams and address the social determinants of health.

CONCLUSION: Addressing knowledge and practice gaps in intermediate and high-risk PE management must be prioritized and informed by forthcoming high-quality data. Implementation efforts are needed to improve acute PE management and resolve treatment disparities.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:31

Enthalten in:

Academic emergency medicine : official journal of the Society for Academic Emergency Medicine - 31(2024), 3 vom: 01. März, Seite 288-292

Sprache:

Englisch

Beteiligte Personen:

Casey, Scott D [VerfasserIn]
Stubblefield, William B [VerfasserIn]
Luijten, Dieuwke [VerfasserIn]
Klok, Frederikus A [VerfasserIn]
Westafer, Lauren M [VerfasserIn]
Vinson, David R [VerfasserIn]
Kabrhel, Christopher [VerfasserIn]

Links:

Volltext

Themen:

Catheter directed thrombolysis
Fibrinolytic Agents
Health care disparities
Journal Article
Pulmonary embolism
Quality improvement
Systemic thrombolysis

Anmerkungen:

Date Completed 14.03.2024

Date Revised 27.04.2024

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1111/acem.14859

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM366206265