Association between hair trace element and all-cause death in elderly people in Hainan
Objective: To explore the association between hair trace element and all-cause death in the elderly in Hainan Province. Methods: The subjects of the study were elderly people from China Hainan Centenarian Cohort Study, a total of 163 elderly were included. The association between hair trace element level and all-cause death was analyzed by using Cox proportional risk regression model. Results: After fully adjusting the covariates, the multiple Cox proportional hazards regression analyses showed that selenium (Se), manganese (Mn), strontium (Sr) concentrations in hair were significantly associated with all-cause mortality, the hazard ratio (HR) were 0.72 (95%CI: 0.54-0.98, P=0.035), 1.50 (95%CI: 1.07-2.11, P=0.020) and 0.54 (95%CI: 0.37-0.79, P=0.001), respectively. Subgroup and cross analysis showed that hair copper (Cu) were significant association with death in the people with anemia, the HR were 1.81 (95%CI: 1.13-2.88, P=0.013). And, hair Mn interacted with anemia, the HR was 0.46 (95%CI: 0.22-0.94, P=0.033). Conclusions: Se, Mn and Sr concentrations in hair were associated with the elevated risk for all-cause death in the elderly in Hainan. Se, Mn and Sr concentrations in hair can be used as a reference index for the prediction of the death risk of long-lived elderly in community, suggesting that the daily diet of elderly people are rich and diverse, in order to maintain normal and balanced trace element content in the body.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:44 |
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| Enthalten in: |
Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi - 44(2023), 12 vom: 10. Dez., Seite 1936-1942 |
| Sprache: |
Chinesisch |
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| Beteiligte Personen: |
Zhu, Q [VerfasserIn] |
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| Links: |
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| Themen: |
42Z2K6ZL8P |
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| Anmerkungen: |
Date Completed 25.12.2023 Date Revised 25.12.2023 published: Print Citation Status MEDLINE |
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| doi: |
10.3760/cma.j.cn112338-20230420-00257 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM366198068 |
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| 245 | 1 | 0 | |a Association between hair trace element and all-cause death in elderly people in Hainan |
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| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Objective: To explore the association between hair trace element and all-cause death in the elderly in Hainan Province. Methods: The subjects of the study were elderly people from China Hainan Centenarian Cohort Study, a total of 163 elderly were included. The association between hair trace element level and all-cause death was analyzed by using Cox proportional risk regression model. Results: After fully adjusting the covariates, the multiple Cox proportional hazards regression analyses showed that selenium (Se), manganese (Mn), strontium (Sr) concentrations in hair were significantly associated with all-cause mortality, the hazard ratio (HR) were 0.72 (95%CI: 0.54-0.98, P=0.035), 1.50 (95%CI: 1.07-2.11, P=0.020) and 0.54 (95%CI: 0.37-0.79, P=0.001), respectively. Subgroup and cross analysis showed that hair copper (Cu) were significant association with death in the people with anemia, the HR were 1.81 (95%CI: 1.13-2.88, P=0.013). And, hair Mn interacted with anemia, the HR was 0.46 (95%CI: 0.22-0.94, P=0.033). Conclusions: Se, Mn and Sr concentrations in hair were associated with the elevated risk for all-cause death in the elderly in Hainan. Se, Mn and Sr concentrations in hair can be used as a reference index for the prediction of the death risk of long-lived elderly in community, suggesting that the daily diet of elderly people are rich and diverse, in order to maintain normal and balanced trace element content in the body | ||
| 650 | 4 | |a English Abstract | |
| 650 | 4 | |a Journal Article | |
| 650 | 7 | |a Trace Elements |2 NLM | |
| 650 | 7 | |a Copper |2 NLM | |
| 650 | 7 | |a 789U1901C5 |2 NLM | |
| 650 | 7 | |a Manganese |2 NLM | |
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| 650 | 7 | |a Selenium |2 NLM | |
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| 700 | 1 | |a Li, J |e verfasserin |4 aut | |
| 700 | 1 | |a Fu, S H |e verfasserin |4 aut | |
| 700 | 1 | |a Ning, C X |e verfasserin |4 aut | |
| 700 | 1 | |a Chen, Y J |e verfasserin |4 aut | |
| 700 | 1 | |a Yang, T |e verfasserin |4 aut | |
| 700 | 1 | |a Zhou, H W |e verfasserin |4 aut | |
| 700 | 1 | |a Liu, M |e verfasserin |4 aut | |
| 700 | 1 | |a He, Y |e verfasserin |4 aut | |
| 700 | 1 | |a Zhao, Y L |e verfasserin |4 aut | |
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