Trends in Lung Cancer Incidence and Mortality (1990-2019) in the United States : A Comprehensive Analysis of Gender and State-Level Disparities
PURPOSE: Lung cancer is the leading cause of cancer-related deaths in the United States. This study aims to analyze lung cancer incidence, mortality, and related statistics from 1990 to 2019, focusing on national- and state-level trends and exploring potential disparities between sexes.
METHODS: The Global Burden of Disease database was used to extract tracheal, bronchus, and lung cancer mortality data from 1990 to 2019 for both males and females and across all states of the United States. Age-standardized incidence rates, age-standardized mortality rates, disability-adjusted life years (DALYs), and mortality-to-incidence indices (MIIs) were studied to assess for gender-based, geographic, and temporal disparities. Joinpoint regression analysis was performed to further evaluate trends.
RESULTS: The incidence of these cancers in the United States decreased between 1990 and 2019 by 23.35%, with a more significant decline in males (37.73%) than females (1.41%). Similarly, for mortality, a decrease was observed for both sexes combined (26.83%), but much more significantly for males (40.23%) than females (6.01%). The MIIs decreased overall, but there were variations across states. DALYs decreased for both sexes combined, with males experiencing a larger reduction, but an increase was noted in some states for females.
CONCLUSION: This analysis reveals diverse trends pertaining to the incidence, mortality, and disability burden associated with lung cancer by sex and states in the United States, emphasizing the need for targeted interventions to reduce disparities. These findings contribute to our understanding of the current landscape of lung cancer and can inform future strategies for prevention, early detection, and management.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2023 |
|---|---|
| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:9 |
|---|---|
| Enthalten in: |
JCO global oncology - 9(2023) vom: 22. Sept., Seite e2300255 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Jani, Chinmay T [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
|---|
| Anmerkungen: |
Date Completed 25.12.2023 Date Revised 29.12.2023 published: Print Citation Status MEDLINE |
|---|
| doi: |
10.1200/GO.23.00255 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM366184334 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM366184334 | ||
| 003 | DE-627 | ||
| 005 | 20240108140025.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231227s2023 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1200/GO.23.00255 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1242.xml |
| 035 | |a (DE-627)NLM366184334 | ||
| 035 | |a (NLM)38127772 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Jani, Chinmay T |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Trends in Lung Cancer Incidence and Mortality (1990-2019) in the United States |b A Comprehensive Analysis of Gender and State-Level Disparities |
| 264 | 1 | |c 2023 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 25.12.2023 | ||
| 500 | |a Date Revised 29.12.2023 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a PURPOSE: Lung cancer is the leading cause of cancer-related deaths in the United States. This study aims to analyze lung cancer incidence, mortality, and related statistics from 1990 to 2019, focusing on national- and state-level trends and exploring potential disparities between sexes | ||
| 520 | |a METHODS: The Global Burden of Disease database was used to extract tracheal, bronchus, and lung cancer mortality data from 1990 to 2019 for both males and females and across all states of the United States. Age-standardized incidence rates, age-standardized mortality rates, disability-adjusted life years (DALYs), and mortality-to-incidence indices (MIIs) were studied to assess for gender-based, geographic, and temporal disparities. Joinpoint regression analysis was performed to further evaluate trends | ||
| 520 | |a RESULTS: The incidence of these cancers in the United States decreased between 1990 and 2019 by 23.35%, with a more significant decline in males (37.73%) than females (1.41%). Similarly, for mortality, a decrease was observed for both sexes combined (26.83%), but much more significantly for males (40.23%) than females (6.01%). The MIIs decreased overall, but there were variations across states. DALYs decreased for both sexes combined, with males experiencing a larger reduction, but an increase was noted in some states for females | ||
| 520 | |a CONCLUSION: This analysis reveals diverse trends pertaining to the incidence, mortality, and disability burden associated with lung cancer by sex and states in the United States, emphasizing the need for targeted interventions to reduce disparities. These findings contribute to our understanding of the current landscape of lung cancer and can inform future strategies for prevention, early detection, and management | ||
| 650 | 4 | |a Journal Article | |
| 700 | 1 | |a Singh, Harpreet |e verfasserin |4 aut | |
| 700 | 1 | |a Abdallah, Nour |e verfasserin |4 aut | |
| 700 | 1 | |a Mouchati, Christian |e verfasserin |4 aut | |
| 700 | 1 | |a Arora, Shreya |e verfasserin |4 aut | |
| 700 | 1 | |a Kareff, Samuel |e verfasserin |4 aut | |
| 700 | 1 | |a Salciccioli, Justin |e verfasserin |4 aut | |
| 700 | 1 | |a Thomson, Carey C |e verfasserin |4 aut | |
| 700 | 1 | |a Velcheti, Vamsidhar |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t JCO global oncology |d 2020 |g 9(2023) vom: 22. Sept., Seite e2300255 |w (DE-627)NLM30617877X |x 2687-8941 |7 nnns |
| 773 | 1 | 8 | |g volume:9 |g year:2023 |g day:22 |g month:09 |g pages:e2300255 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1200/GO.23.00255 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 9 |j 2023 |b 22 |c 09 |h e2300255 | ||