Unexplained subfertility : active or conservative management?
© 2023 Walter de Gruyter GmbH, Berlin/Boston..
OBJECTIVES: Unexplained subfertility (UEI) describes a couple whose standard subfertility workout consider acceptable but unable to conceived.
METHODS: This retrospective study was conducted in the Advanced Reproductive Centre, UKM Hospital, Kuala Lumpur, from January 2016 to December 2019. The data of 268 UEI couples were obtained from the clinical database. Women aged 21-45 years old was included and further divided into four groups according to the female partner's age and subfertility duration: group A (age <35 years and subfertility <2 years), group B (age <35 years and subfertility >2 years), group C (age >35 years and subfertility <2 years), and group D (age >35 years and subfertility <2 years). All statistical analyses were performed using SPSS 22.0 for Windows.
RESULTS: A total of 255 cases were included in this study. The mean age of the women was 32.9 ± 4.04 years, and the mean subfertility duration was 5.04 ± 2.9 years. A total of 51 (20 %) cases underwent timed sexual intercourse, 147 (57.6 %) cases had intrauterine insemination (IUI), whereas 57 (22.4 %) cases opted for in vitro fertilization (IVF). A total of 204 cases underwent active management (IUI/IVF), which showed a significant difference (p<0.05). Out of eight clinical pregnancies, half of them were from group B.
CONCLUSIONS: Active management in younger women with a shorter subfertility duration revealed a better pregnancy outcome. Otherwise, individualized treatment should be considered in selecting a suitable treatment plan.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2023 |
|---|---|
| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:44 |
|---|---|
| Enthalten in: |
Hormone molecular biology and clinical investigation - 44(2023), 4 vom: 01. Dez., Seite 379-384 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Ahmad, Siti Maisarah [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Active management |
|---|
| Anmerkungen: |
Date Completed 01.02.2024 Date Revised 01.02.2024 published: Electronic-eCollection Citation Status MEDLINE |
|---|
| doi: |
10.1515/hmbci-2022-0087 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM36615334X |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM36615334X | ||
| 003 | DE-627 | ||
| 005 | 20240201232054.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231227s2023 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1515/hmbci-2022-0087 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1277.xml |
| 035 | |a (DE-627)NLM36615334X | ||
| 035 | |a (NLM)38124670 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Ahmad, Siti Maisarah |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Unexplained subfertility |b active or conservative management? |
| 264 | 1 | |c 2023 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 01.02.2024 | ||
| 500 | |a Date Revised 01.02.2024 | ||
| 500 | |a published: Electronic-eCollection | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2023 Walter de Gruyter GmbH, Berlin/Boston. | ||
| 520 | |a OBJECTIVES: Unexplained subfertility (UEI) describes a couple whose standard subfertility workout consider acceptable but unable to conceived | ||
| 520 | |a METHODS: This retrospective study was conducted in the Advanced Reproductive Centre, UKM Hospital, Kuala Lumpur, from January 2016 to December 2019. The data of 268 UEI couples were obtained from the clinical database. Women aged 21-45 years old was included and further divided into four groups according to the female partner's age and subfertility duration: group A (age <35 years and subfertility <2 years), group B (age <35 years and subfertility >2 years), group C (age >35 years and subfertility <2 years), and group D (age >35 years and subfertility <2 years). All statistical analyses were performed using SPSS 22.0 for Windows | ||
| 520 | |a RESULTS: A total of 255 cases were included in this study. The mean age of the women was 32.9 ± 4.04 years, and the mean subfertility duration was 5.04 ± 2.9 years. A total of 51 (20 %) cases underwent timed sexual intercourse, 147 (57.6 %) cases had intrauterine insemination (IUI), whereas 57 (22.4 %) cases opted for in vitro fertilization (IVF). A total of 204 cases underwent active management (IUI/IVF), which showed a significant difference (p<0.05). Out of eight clinical pregnancies, half of them were from group B | ||
| 520 | |a CONCLUSIONS: Active management in younger women with a shorter subfertility duration revealed a better pregnancy outcome. Otherwise, individualized treatment should be considered in selecting a suitable treatment plan | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a active management | |
| 650 | 4 | |a intrauterine insemination | |
| 650 | 4 | |a in vitro fertilisation | |
| 650 | 4 | |a unexplained infertility | |
| 650 | 4 | |a women | |
| 700 | 1 | |a Mat Jin, Norazilah |e verfasserin |4 aut | |
| 700 | 1 | |a Ahmad, Mohd Faizal |e verfasserin |4 aut | |
| 700 | 1 | |a Abdul Karim, Abdul Kadir |e verfasserin |4 aut | |
| 700 | 1 | |a Abu, Muhammad Azrai |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Hormone molecular biology and clinical investigation |d 2010 |g 44(2023), 4 vom: 01. Dez., Seite 379-384 |w (DE-627)NLM205276490 |x 1868-1891 |7 nnns |
| 773 | 1 | 8 | |g volume:44 |g year:2023 |g number:4 |g day:01 |g month:12 |g pages:379-384 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1515/hmbci-2022-0087 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 44 |j 2023 |e 4 |b 01 |c 12 |h 379-384 | ||