Cardio-renal-metabolic disease in primary care setting

© 2023 John Wiley & Sons Ltd..

In the primary care setting providers have more tools available than ever before to impact positively obesity, diabetes, and their complications, such as renal and cardiac diseases. It is important to recognise what is available for treatment taking into account diabetes heterogeneity. For those who develop type 2 diabetes (T2DM), effective treatments are available that for the first time have shown a benefit in reducing mortality and macrovascular complications, in addition to the well-established benefits of glucose control in reducing microvascular complications. Some of the newer medications for treating hyperglycaemia have also a positive impact in reducing heart failure (HF). Technological advances have also contributed to improving the quality of care in patients with diabetes. The use of technology, such as continuous glucose monitoring systems (CGM), has improved significantly glucose and glycated haemoglobin A1c (HbA1c) values, while limiting the frequency of hypoglycaemia. Other technological support derives from the use of predictive algorithms that need to be refined to help predict those subjects who are at great risk of developing the disease and/or its complications, or who may require care by other specialists. In this review we also provide recommendations for the optimal use of the new medications; sodium-glucose co-transporter-2 inhibitors (SGLT2i) and Glucagon-like peptide-receptor agonists 1 (GLP1RA) in the primary care setting considering the relevance of these drugs for the management of T2DM also in its early stage.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:40

Enthalten in:

Diabetes/metabolism research and reviews - 40(2024), 3 vom: 01. März, Seite e3755

Sprache:

Englisch

Beteiligte Personen:

Ibrahim, Mahmoud [VerfasserIn]
Ba-Essa, Ebtesam M [VerfasserIn]
Baker, Jason [VerfasserIn]
Cahn, Avivit [VerfasserIn]
Ceriello, Antonio [VerfasserIn]
Cosentino, Francesco [VerfasserIn]
Davies, Melanie J [VerfasserIn]
Eckel, Robert H [VerfasserIn]
Van Gaal, Luc [VerfasserIn]
Gaede, Peter [VerfasserIn]
Handelsman, Yehuda [VerfasserIn]
Klein, Samuel [VerfasserIn]
Leslie, Richard David [VerfasserIn]
Pozzilli, Paolo [VerfasserIn]
Del Prato, Stefano [VerfasserIn]
Prattichizzo, Francesco [VerfasserIn]
Schnell, Oliver [VerfasserIn]
Seferovic, Petar M [VerfasserIn]
Standl, Eberhard [VerfasserIn]
Thomas, Abraham [VerfasserIn]
Tuomilehto, Jaakko [VerfasserIn]
Valensi, Paul [VerfasserIn]
Umpierrez, Guillermo E [VerfasserIn]

Links:

Volltext

Themen:

89750-14-1
Blood Glucose
CVOTs
Chronic kidney disease
Glucagon-Like Peptide 1
Glucagon-Like Peptide-1 Receptor
Heart failure
Hypoglycemic Agents
Journal Article
Obesity
Review
Sodium-Glucose Transporter 2 Inhibitors
Technology
Type 2 diabetes

Anmerkungen:

Date Completed 14.03.2024

Date Revised 14.03.2024

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1002/dmrr.3755

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM366063839