An unusual case of Takayasu arteritis presenting with persistent cough in a young female patient : A case report
© 2023 The Authors. Published by Elsevier Inc. on behalf of University of Washington..
Takayasu arteritis (TA) is a chronic granulomatous inflammatory arteritis of large vessels. Females aged 20-40 are usually affected and the manifestations can range from asymptomatic disease to major cardiovascular and neurological abnormalities. Herein, we present a case of a 20-year-old female who had a persistent cough as the initial manifestation of an underlying TA. She had a free past medical history. The patient sought medical help multiple times and took many antibiotics with no improvement. Laboratory tests showed a marked elevation in inflammatory markers so the patient was admitted for further investigations. CT scan showed a circumferential mural thickening involving mainly the descending thoracic aorta which is highly suggestive of an underlying chronic granulomatous vasculitis behind this. Our patient was treated with a combination of corticosteroid and azathioprine and showed substantial improvement after 2 weeks. TA can present with various symptoms. Therefore, patients presenting with atypical symptoms and late-onset vascular symptoms need a high degree of suspicion with close follow-up to allow early detection of any complication.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2024 2023 |
|---|---|
| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:19 |
|---|---|
| Enthalten in: |
Radiology case reports - 19(2023), 2 vom: 28. Feb., Seite 651-653 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Ameerah, Yara [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Aorta |
|---|
| Anmerkungen: |
Date Revised 20.12.2023 published: Electronic-eCollection Citation Status PubMed-not-MEDLINE |
|---|
| doi: |
10.1016/j.radcr.2023.11.009 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM366022490 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM366022490 | ||
| 003 | DE-627 | ||
| 005 | 20231227134949.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231227s2024 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.radcr.2023.11.009 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1233.xml |
| 035 | |a (DE-627)NLM366022490 | ||
| 035 | |a (NLM)38111545 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Ameerah, Yara |e verfasserin |4 aut | |
| 245 | 1 | 3 | |a An unusual case of Takayasu arteritis presenting with persistent cough in a young female patient |b A case report |
| 264 | 1 | |c 2024 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Revised 20.12.2023 | ||
| 500 | |a published: Electronic-eCollection | ||
| 500 | |a Citation Status PubMed-not-MEDLINE | ||
| 520 | |a © 2023 The Authors. Published by Elsevier Inc. on behalf of University of Washington. | ||
| 520 | |a Takayasu arteritis (TA) is a chronic granulomatous inflammatory arteritis of large vessels. Females aged 20-40 are usually affected and the manifestations can range from asymptomatic disease to major cardiovascular and neurological abnormalities. Herein, we present a case of a 20-year-old female who had a persistent cough as the initial manifestation of an underlying TA. She had a free past medical history. The patient sought medical help multiple times and took many antibiotics with no improvement. Laboratory tests showed a marked elevation in inflammatory markers so the patient was admitted for further investigations. CT scan showed a circumferential mural thickening involving mainly the descending thoracic aorta which is highly suggestive of an underlying chronic granulomatous vasculitis behind this. Our patient was treated with a combination of corticosteroid and azathioprine and showed substantial improvement after 2 weeks. TA can present with various symptoms. Therefore, patients presenting with atypical symptoms and late-onset vascular symptoms need a high degree of suspicion with close follow-up to allow early detection of any complication | ||
| 650 | 4 | |a Case Reports | |
| 650 | 4 | |a Aorta | |
| 650 | 4 | |a Case report | |
| 650 | 4 | |a Cough | |
| 650 | 4 | |a Immunosuppressant | |
| 650 | 4 | |a Takayasu arteritis | |
| 700 | 1 | |a Moghrabi, Serin |e verfasserin |4 aut | |
| 700 | 1 | |a Awadghanem, Ahmed |e verfasserin |4 aut | |
| 700 | 1 | |a Hanbali, Rifat |e verfasserin |4 aut | |
| 700 | 1 | |a Maree, Mosab |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Radiology case reports |d 2006 |g 19(2023), 2 vom: 28. Feb., Seite 651-653 |w (DE-627)NLM255395299 |x 1930-0433 |7 nnns |
| 773 | 1 | 8 | |g volume:19 |g year:2023 |g number:2 |g day:28 |g month:02 |g pages:651-653 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1016/j.radcr.2023.11.009 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 19 |j 2023 |e 2 |b 28 |c 02 |h 651-653 | ||