First Molecular Evidence of Emerging Lophomonas Pathogen Among Patients Suspected of Having Pulmonary Tuberculosis in Mazandaran Province, Northern Iran
© 2023. The Author(s), under exclusive licence to Springer Nature Switzerland AG..
PURPOSE: Lophomoniasis is a chronic protozoan respiratory disease in humans with main clinical symptoms such as chronic cough, productive sputum, breath shortness, and occasionally hemoptysis. Differentiation diagnosis of lophomoniasis from tuberculosis (TB) and asthma is crucial.
METHODS: In this study, 210 participants with suspected TB referred to tuberculosis laboratories in Mazandaran province, northeastern Iran, were enrolled during 2021. All patients showed low grade fever, chronic cough or sputum on referral. Sputum specimens were collected from the participants, and Lophomonas DNA was detected through a conventional genus-specific polymerase chain reaction (PCR).
RESULTS: Out of 210 participants, 67 (31.9%) had Lophomonas spp., infection, 38 (18.1%) had TB (Smear and culture-positive), and 20 (9.5%) had both TB and Lophomonas co-infection.
CONCLUSION: Based on our results, a relatively high occurrence of Lophomonas infection was found among patients suspected of having TB. Accordingly, due to the high similarity of clinical symptoms between both pulmonary diseases, it is highly recommended to accurately and early diagnose the parasite in the sputum specimen.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2023 |
|---|---|
| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - year:2023 |
|---|---|
| Enthalten in: |
Acta parasitologica - (2023) vom: 18. Dez. |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Veisi, Hossein [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Co-morbidity |
|---|
| Anmerkungen: |
Date Revised 19.12.2023 published: Print-Electronic Citation Status Publisher |
|---|
| doi: |
10.1007/s11686-023-00729-3 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM366013416 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM366013416 | ||
| 003 | DE-627 | ||
| 005 | 20231227134617.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231227s2023 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1007/s11686-023-00729-3 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1232.xml |
| 035 | |a (DE-627)NLM366013416 | ||
| 035 | |a (NLM)38110641 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Veisi, Hossein |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a First Molecular Evidence of Emerging Lophomonas Pathogen Among Patients Suspected of Having Pulmonary Tuberculosis in Mazandaran Province, Northern Iran |
| 264 | 1 | |c 2023 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Revised 19.12.2023 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status Publisher | ||
| 520 | |a © 2023. The Author(s), under exclusive licence to Springer Nature Switzerland AG. | ||
| 520 | |a PURPOSE: Lophomoniasis is a chronic protozoan respiratory disease in humans with main clinical symptoms such as chronic cough, productive sputum, breath shortness, and occasionally hemoptysis. Differentiation diagnosis of lophomoniasis from tuberculosis (TB) and asthma is crucial | ||
| 520 | |a METHODS: In this study, 210 participants with suspected TB referred to tuberculosis laboratories in Mazandaran province, northeastern Iran, were enrolled during 2021. All patients showed low grade fever, chronic cough or sputum on referral. Sputum specimens were collected from the participants, and Lophomonas DNA was detected through a conventional genus-specific polymerase chain reaction (PCR) | ||
| 520 | |a RESULTS: Out of 210 participants, 67 (31.9%) had Lophomonas spp., infection, 38 (18.1%) had TB (Smear and culture-positive), and 20 (9.5%) had both TB and Lophomonas co-infection | ||
| 520 | |a CONCLUSION: Based on our results, a relatively high occurrence of Lophomonas infection was found among patients suspected of having TB. Accordingly, due to the high similarity of clinical symptoms between both pulmonary diseases, it is highly recommended to accurately and early diagnose the parasite in the sputum specimen | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Co-morbidity | |
| 650 | 4 | |a Lophomonas | |
| 650 | 4 | |a PCR | |
| 650 | 4 | |a Pulmonary tuberculosis | |
| 650 | 4 | |a Sputum | |
| 700 | 1 | |a Malakian, Abdollah |e verfasserin |4 aut | |
| 700 | 1 | |a Fakhar, Mahdi |e verfasserin |4 aut | |
| 700 | 1 | |a Sharifpour, Ali |e verfasserin |4 aut | |
| 700 | 1 | |a Nakhaei, Maryam |e verfasserin |4 aut | |
| 700 | 1 | |a Soleymani, Mostafa |e verfasserin |4 aut | |
| 700 | 1 | |a Mosave, Seyed Reza |e verfasserin |4 aut | |
| 700 | 1 | |a Ahangar, Nader |e verfasserin |4 aut | |
| 700 | 1 | |a Seyedpour, Seyed Hosien |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Acta parasitologica |d 1989 |g (2023) vom: 18. Dez. |w (DE-627)NLM09254536X |x 1896-1851 |7 nnns |
| 773 | 1 | 8 | |g year:2023 |g day:18 |g month:12 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1007/s11686-023-00729-3 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |j 2023 |b 18 |c 12 | ||