Simultaneous detection of three nitrofuran antibiotics by the lateral flow immunoassay based on europium nanoparticles in aquatic products

Copyright © 2023 Elsevier Ltd. All rights reserved..

Nitrofuran (NF) antibiotics have been banned worldwide in aquaculture due to their potential carcinogenicity and mutagenicity. Because of the short half-life of NF antibiotics, an easy and sensitive multiple lateral flow immunoassay (mLFIA) based on europium nanoparticles (EuNPs) has been successfully established to simultaneously and quantitatively detect 3-amino-5-morpholinomethyl-2-oxazolidinone (AMOZ), 3-amino-2-oxazolidinone (AOZ) and sodium nifurstylenate (NFS) in aquatic products. The EuNP-mLFIA assay was accomplished within 10 min. The limits of detection (LODs) for AOZ, AMOZ and NFS were 0.013, 0.019 and 0.023 ng/mL, respectively. The average recoveries of AOZ, AMOZ and NFS were 98.0-104.4%, 96.0-102.6% and 98.0-102.8%, respectively. It showed satisfactory consistency, and the feasibility was validated by high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS). Briefly, this method will become a powerful tool for monitoring multiple NF antibiotics and provide promising applications in the field of food safety and environmental testing.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:439

Enthalten in:

Food chemistry - 439(2024) vom: 01. Jan., Seite 138171

Sprache:

Englisch

Beteiligte Personen:

Mei, Qing [VerfasserIn]
Ma, Biao [VerfasserIn]
Li, Jiali [VerfasserIn]
Deng, Xin [VerfasserIn]
Shuai, Jiangbing [VerfasserIn]
Zhou, Yuxin [VerfasserIn]
Zhang, Mingzhou [VerfasserIn]

Links:

Volltext

Themen:

444W947O8O
Anti-Bacterial Agents
Aquatic products
Europium
Europium nanoparticles
Journal Article
Lateral flow immunoassay
Multiple detection
Nitrofuran metabolites
Nitrofurans

Anmerkungen:

Date Completed 10.01.2024

Date Revised 10.01.2024

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1016/j.foodchem.2023.138171

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM365915653