Vancomycin-resistant Enterococcus faecium in Japan, 2007-2015 : a molecular epidemiology analysis focused on examining strain characteristics over time
IMPORTANCE: Our study emphasizes the efficacy of whole-genome sequencing (WGS) in addressing outbreaks of vancomycin-resistant enterococci. WGS enables the identification and tracking of resistant bacterial strains, early detection and management of novel infectious disease outbreaks, and the appropriate selection and use of antibiotics. Furthermore, our approach deepens our understanding of how resistant bacteria transfer genes and adapt to their environments or hosts. For modern medicine, these insights have significant implications for controlling infections and effectively managing antibiotic use in the current era, where antibiotic resistance is progressing.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:12 |
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| Enthalten in: |
Microbiology spectrum - 12(2024), 1 vom: 11. Jan., Seite e0244423 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Tokano, Mieko [VerfasserIn] |
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| Links: |
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| Anmerkungen: |
Date Completed 15.01.2024 Date Revised 15.01.2024 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1128/spectrum.02444-23 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM365908576 |
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| 520 | |a IMPORTANCE: Our study emphasizes the efficacy of whole-genome sequencing (WGS) in addressing outbreaks of vancomycin-resistant enterococci. WGS enables the identification and tracking of resistant bacterial strains, early detection and management of novel infectious disease outbreaks, and the appropriate selection and use of antibiotics. Furthermore, our approach deepens our understanding of how resistant bacteria transfer genes and adapt to their environments or hosts. For modern medicine, these insights have significant implications for controlling infections and effectively managing antibiotic use in the current era, where antibiotic resistance is progressing | ||
| 650 | 4 | |a Journal Article | |
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| 650 | 4 | |a Tn1546 transposons | |
| 650 | 4 | |a multilocus sequence typing (MLST) | |
| 650 | 4 | |a plasmid analysis | |
| 650 | 4 | |a pulsed-field gel electrophoresis (PFGE) | |
| 650 | 4 | |a vancomycin-resistant enterococci (VRE) | |
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| 700 | 1 | |a Tarumoto, Norihito |e verfasserin |4 aut | |
| 700 | 1 | |a Sakai, Jun |e verfasserin |4 aut | |
| 700 | 1 | |a Imai, Kazuo |e verfasserin |4 aut | |
| 700 | 1 | |a Kodana, Masahiro |e verfasserin |4 aut | |
| 700 | 1 | |a Kawamura, Toru |e verfasserin |4 aut | |
| 700 | 1 | |a Maeda, Takuya |e verfasserin |4 aut | |
| 700 | 1 | |a Maesaki, Shigefumi |e verfasserin |4 aut | |
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