Prognostic factors and survival in adult acute leukemia in Burkina Faso
Copyright © 2023 SFMTSI..
Introduction: Acute leukemia is both a diagnostic and therapeutic emergency. Our study aimed to describe the prognostic factors and survival of adults with acute leukemia in Burkina Faso.
Patients and methods: Cross-sectional descriptive study with retrospective data collection covering a period of 4.5 years (2018-2022) in two university hospitals in Burkina Faso. Were included all patients over 18 years hospitalized for acute leukemia in these sites with a usable medical record.
Results: A total of 42 cases were collected, of which 45% suffered from acute lymphoblastic leukemia and 43% from acute myeloid leukemia. In 12% of cases, acute leukemia was not classified. The average age was 35 ± 15 years, with extremes of 19 and 72 years. 12% of the patients presented an age of poor prognosis. Comorbidities were present in 14% of patients. The deterioration in general condition was fairly constant with 95% of patients at WHO stages 3 and 4. All patients presented with bone marrow failure syndrome and tumor syndrome was found in 45%. Anemia and thrombocytopenia were present in almost all cases. Hyperleukocytosis at diagnosis was present in 28 patients (67%); among them 18 patients (64%) had leukocytes greater than 50 G/L. Death in hospital was found in 38% of patients and loss of sight in 31%. The median survival was 3 months. Survival was 30% at 6 months and 0% at 12 months.
Conclusion: Acute leukemias are in our practice conditions of poor prognosis with a fairly short survival.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:3 |
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| Enthalten in: |
Medecine tropicale et sante internationale - 3(2023), 3 vom: 30. Sept. |
| Sprache: |
Französisch |
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| Weiterer Titel: |
Facteurs pronostiques et survie des leucémies aiguës de l'adulte au Burkina Faso |
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| Beteiligte Personen: |
Traoré, Catherine [VerfasserIn] |
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| Links: |
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| Themen: |
Acute leukemia |
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| Anmerkungen: |
Date Completed 16.12.2023 Date Revised 27.02.2024 published: Electronic-eCollection Citation Status MEDLINE |
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| doi: |
10.48327/mtsi.v3i3.2023.409 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| 100 | 1 | |a Traoré, Catherine |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Prognostic factors and survival in adult acute leukemia in Burkina Faso |
| 246 | 3 | 3 | |a Facteurs pronostiques et survie des leucémies aiguës de l'adulte au Burkina Faso |
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| 500 | |a Date Revised 27.02.2024 | ||
| 500 | |a published: Electronic-eCollection | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2023 SFMTSI. | ||
| 520 | |a Introduction: Acute leukemia is both a diagnostic and therapeutic emergency. Our study aimed to describe the prognostic factors and survival of adults with acute leukemia in Burkina Faso | ||
| 520 | |a Patients and methods: Cross-sectional descriptive study with retrospective data collection covering a period of 4.5 years (2018-2022) in two university hospitals in Burkina Faso. Were included all patients over 18 years hospitalized for acute leukemia in these sites with a usable medical record | ||
| 520 | |a Results: A total of 42 cases were collected, of which 45% suffered from acute lymphoblastic leukemia and 43% from acute myeloid leukemia. In 12% of cases, acute leukemia was not classified. The average age was 35 ± 15 years, with extremes of 19 and 72 years. 12% of the patients presented an age of poor prognosis. Comorbidities were present in 14% of patients. The deterioration in general condition was fairly constant with 95% of patients at WHO stages 3 and 4. All patients presented with bone marrow failure syndrome and tumor syndrome was found in 45%. Anemia and thrombocytopenia were present in almost all cases. Hyperleukocytosis at diagnosis was present in 28 patients (67%); among them 18 patients (64%) had leukocytes greater than 50 G/L. Death in hospital was found in 38% of patients and loss of sight in 31%. The median survival was 3 months. Survival was 30% at 6 months and 0% at 12 months | ||
| 520 | |a Conclusion: Acute leukemias are in our practice conditions of poor prognosis with a fairly short survival | ||
| 650 | 4 | |a English Abstract | |
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Acute leukemia | |
| 650 | 4 | |a Adult | |
| 650 | 4 | |a Burkina Faso | |
| 650 | 4 | |a Prognosis | |
| 650 | 4 | |a Sub-Saharan Africa | |
| 650 | 4 | |a Survival | |
| 700 | 1 | |a Nebié, Koumpingnin |e verfasserin |4 aut | |
| 700 | 1 | |a Sawadogo, Salam |e verfasserin |4 aut | |
| 700 | 1 | |a Sanou, Adjaratou Fabienne |e verfasserin |4 aut | |
| 700 | 1 | |a Héma, Arsène |e verfasserin |4 aut | |
| 700 | 1 | |a Kafando, Éléonore |e verfasserin |4 aut | |
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