Lymphocyte and neutrophil count combined with intestinal bacteria abundance predict the severity of COVID-19
IMPORTANCE: The 2019 coronavirus disease (COVID-19) patients had a unique profile of gut bacteria. In this study, we characterized the intestinal bacteria in our COVID-19 cohorts and found that there was an increased incidence of severe cases in COVID-19 patients with decreased lymphocytes and increased neutrophils. Levels of lymphocytes and neutrophils and abundances of intestinal bacteria correlated with the severity of COVID-19.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:12 |
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| Enthalten in: |
Microbiology spectrum - 12(2024), 1 vom: 11. Jan., Seite e0302723 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Chen, Liuying [VerfasserIn] |
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| Links: |
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| Themen: |
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| Anmerkungen: |
Date Completed 15.01.2024 Date Revised 15.01.2024 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1128/spectrum.03027-23 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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NLM365792713 |
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| 520 | |a IMPORTANCE: The 2019 coronavirus disease (COVID-19) patients had a unique profile of gut bacteria. In this study, we characterized the intestinal bacteria in our COVID-19 cohorts and found that there was an increased incidence of severe cases in COVID-19 patients with decreased lymphocytes and increased neutrophils. Levels of lymphocytes and neutrophils and abundances of intestinal bacteria correlated with the severity of COVID-19 | ||
| 650 | 4 | |a Journal Article | |
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| 650 | 4 | |a neutrophils | |
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| 700 | 1 | |a Yu, Cheng |e verfasserin |4 aut | |
| 700 | 1 | |a Luo, Chang |e verfasserin |4 aut | |
| 700 | 1 | |a Jin, Yu |e verfasserin |4 aut | |
| 700 | 1 | |a Zhang, Lei |e verfasserin |4 aut | |
| 700 | 1 | |a Song, Jun |e verfasserin |4 aut | |
| 700 | 1 | |a Rasche, Leo |e verfasserin |4 aut | |
| 700 | 1 | |a Einsele, Hermann |e verfasserin |4 aut | |
| 700 | 1 | |a Tu, Lei |e verfasserin |4 aut | |
| 700 | 1 | |a Zhou, Xiang |e verfasserin |4 aut | |
| 700 | 1 | |a Bai, Tao |e verfasserin |4 aut | |
| 700 | 1 | |a Hou, Xiaohua |e verfasserin |4 aut | |
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