Therapeutic potential of propolis in alleviating inflammatory response and promoting wound healing in skin burn

© 2023 John Wiley & Sons Ltd..

Burns can cause inflammation and delayed healing, necessitating alternative therapies due to the limitations of conventional treatments. Propolis, a natural bee-produced substance, has shown promise in facilitating burn healing. This literature review provides a comprehensive overview of propolis' mechanisms of action, wound-healing properties, and its application in treating skin burns. Propolis contains bioactive compounds with antimicrobial, antioxidant, and anti-inflammatory properties, making it a promising candidate for managing skin burn injuries. It helps prevent infections, neutralize harmful free radicals, and promote a well-balanced inflammatory response. Moreover, propolis aids in wound closure, tissue regeneration, collagen synthesis, cellular proliferation, and angiogenesis, contributing to tissue regeneration and remodeling. The article discusses various propolis extracts, extraction methods, chemical composition, and optimized formulations like ointments and creams for burn wound treatment. Considerations regarding dosage and safety are addressed. Further research is needed to fully understand propolis' mechanisms, determine optimal formulations, and establish suitable clinical dosages. Nevertheless, propolis' natural origin and demonstrated benefits make it a compelling avenue for burn care exploration, potentially complementing existing therapies and improving burn management outcomes.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:38

Enthalten in:

Phytotherapy research : PTR - 38(2024), 2 vom: 09. Feb., Seite 856-879

Sprache:

Englisch

Beteiligte Personen:

Manginstar, Christian Oktavianus [VerfasserIn]
Tallei, Trina Ekawati [VerfasserIn]
Niode, Nurdjannah Jane [VerfasserIn]
Salaki, Christina Leta [VerfasserIn]
Hessel, Sofia Safitri [VerfasserIn]

Links:

Volltext

Themen:

9009-62-5
Alternative therapies
Anti-Infective Agents
Anti-Inflammatory Agents
Inflammation
Journal Article
Propolis
Review
Skin burns
Wound healing

Anmerkungen:

Date Completed 15.02.2024

Date Revised 15.02.2024

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1002/ptr.8092

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM365755788