Epidemiological, clinical, and functional characteristics of patients older than 75 years admitted to a tertiary hospital during the first wave of the SARS-CoV-2 pandemic
Copyright © 2023 SEGG. Publicado por Elsevier España, S.L.U. All rights reserved..
BACKGROUND: The objective of the present study is to analyze the epidemiological, clinical and functional characteristics of patients admitted to the University Hospital of Navarra due to SARS-CoV-2 infection, as well as the predictors of mortality, during the first wave of the pandemic caused by this virus.
METHODOLOGY: An observational, retrospective study was performed, including all hospitalized patients older than 75 years. Information has been obtained on multiple variables, among which it is worth mentioning previous geriatric syndromes or those that have appeared during hospitalization, or past medical history considered relevant in SARS-CoV-2 infection. A descriptive analysis of the data, comparisons according to various factors of interest and multivariate analysis to analyze factors associated with mortality were carried out.
RESULTS: Data have been obtained from a total of 426 patients with a mean age of 83.2 years (52.6% men). 34.7% died in hospital and 4.5% within 1 month after hospital discharge. The factors related to mortality were: worse baseline functional status, chronic kidney disease, and fever or dyspnea as forms of presentation. The most frequent typical symptoms were: fever, dyspnea, cough, asthenia and hyporexia. Up to 42.1% presented delirium as a symptom of atypical onset. We observed a functional deterioration that was not recover after a month of follow-up (baseline Barthel index 81.12; 70.08 at discharge; 75.55 after a month).
CONCLUSIONS: SARS-CoV-2 infection has caused high mortality rates in older adults. In this age group, the atypical presentation of this disease and functional deterioration during hospitalization are frequent. In the present study, a worse previous functional status has been identified as a predictor of mortality. More studies are needed to evaluate the impact that the disease and hospitalization have on the older patient, with the aim of implementing preventive, diagnostic and therapeutic measures that are necessary to avoid functional deterioration and adverse health events related to it.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2024 |
|---|---|
| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:59 |
|---|---|
| Enthalten in: |
Revista espanola de geriatria y gerontologia - 59(2024), 2 vom: 01. März, Seite 101449 |
| Sprache: |
Spanisch |
|---|
| Weiterer Titel: |
Características epidemiológicas, clínicas y funcionales de los pacientes mayores de 75 años ingresados en un hospital terciario durante la primera ola pandémica por SARS-CoV-2 |
|---|
| Beteiligte Personen: |
Chenhuichen, Chenhui [VerfasserIn] |
|---|
| Links: |
|---|
| Anmerkungen: |
Date Completed 04.03.2024 Date Revised 04.03.2024 published: Print-Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1016/j.regg.2023.101449 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM365557285 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM365557285 | ||
| 003 | DE-627 | ||
| 005 | 20240304232113.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231226s2024 xx |||||o 00| ||spa c | ||
| 024 | 7 | |a 10.1016/j.regg.2023.101449 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1316.xml |
| 035 | |a (DE-627)NLM365557285 | ||
| 035 | |a (NLM)38064873 | ||
| 035 | |a (PII)S0211-139X(23)00170-1 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a spa | ||
| 100 | 1 | |a Chenhuichen, Chenhui |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Epidemiological, clinical, and functional characteristics of patients older than 75 years admitted to a tertiary hospital during the first wave of the SARS-CoV-2 pandemic |
| 246 | 3 | 3 | |a Características epidemiológicas, clínicas y funcionales de los pacientes mayores de 75 años ingresados en un hospital terciario durante la primera ola pandémica por SARS-CoV-2 |
| 264 | 1 | |c 2024 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 04.03.2024 | ||
| 500 | |a Date Revised 04.03.2024 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2023 SEGG. Publicado por Elsevier España, S.L.U. All rights reserved. | ||
| 520 | |a BACKGROUND: The objective of the present study is to analyze the epidemiological, clinical and functional characteristics of patients admitted to the University Hospital of Navarra due to SARS-CoV-2 infection, as well as the predictors of mortality, during the first wave of the pandemic caused by this virus | ||
| 520 | |a METHODOLOGY: An observational, retrospective study was performed, including all hospitalized patients older than 75 years. Information has been obtained on multiple variables, among which it is worth mentioning previous geriatric syndromes or those that have appeared during hospitalization, or past medical history considered relevant in SARS-CoV-2 infection. A descriptive analysis of the data, comparisons according to various factors of interest and multivariate analysis to analyze factors associated with mortality were carried out | ||
| 520 | |a RESULTS: Data have been obtained from a total of 426 patients with a mean age of 83.2 years (52.6% men). 34.7% died in hospital and 4.5% within 1 month after hospital discharge. The factors related to mortality were: worse baseline functional status, chronic kidney disease, and fever or dyspnea as forms of presentation. The most frequent typical symptoms were: fever, dyspnea, cough, asthenia and hyporexia. Up to 42.1% presented delirium as a symptom of atypical onset. We observed a functional deterioration that was not recover after a month of follow-up (baseline Barthel index 81.12; 70.08 at discharge; 75.55 after a month) | ||
| 520 | |a CONCLUSIONS: SARS-CoV-2 infection has caused high mortality rates in older adults. In this age group, the atypical presentation of this disease and functional deterioration during hospitalization are frequent. In the present study, a worse previous functional status has been identified as a predictor of mortality. More studies are needed to evaluate the impact that the disease and hospitalization have on the older patient, with the aim of implementing preventive, diagnostic and therapeutic measures that are necessary to avoid functional deterioration and adverse health events related to it | ||
| 650 | 4 | |a Case Reports | |
| 650 | 4 | |a Observational Study | |
| 650 | 4 | |a English Abstract | |
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Aged | |
| 650 | 4 | |a Anciano | |
| 650 | 4 | |a Determinants of mortality | |
| 650 | 4 | |a Diagnóstico precoz | |
| 650 | 4 | |a Early diagnosis | |
| 650 | 4 | |a Estado funcional | |
| 650 | 4 | |a Factores determinantes de mortalidad | |
| 650 | 4 | |a Functional status | |
| 650 | 4 | |a SARS-CoV-2 | |
| 700 | 1 | |a Marín-Epelde, Itxaso |e verfasserin |4 aut | |
| 700 | 1 | |a Ramón-Espinoza, Fernanda |e verfasserin |4 aut | |
| 700 | 1 | |a Sánchez-Latorre, Marina |e verfasserin |4 aut | |
| 700 | 1 | |a Gonzales Montejo, Nancy Janette |e verfasserin |4 aut | |
| 700 | 1 | |a Pozo Vico, Ana |e verfasserin |4 aut | |
| 700 | 1 | |a Librero López, Julián |e verfasserin |4 aut | |
| 700 | 1 | |a Casas-Herrero, Alvaro |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Revista espanola de geriatria y gerontologia |d 1990 |g 59(2024), 2 vom: 01. März, Seite 101449 |w (DE-627)NLM079842461 |x 1578-1747 |7 nnns |
| 773 | 1 | 8 | |g volume:59 |g year:2024 |g number:2 |g day:01 |g month:03 |g pages:101449 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1016/j.regg.2023.101449 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 59 |j 2024 |e 2 |b 01 |c 03 |h 101449 | ||