Predictive power of isolated high home systolic blood pressure for cardiovascular outcomes in individuals with type 2 diabetes mellitus : KAMOGAWA-HBP study

AIMS/INTRODUCTION: Isolated high home systolic blood pressure (IHHSBP) is a risk for cardiovascular disease (CVD). However, no study has shown an association between IHHSBP and CVD in diabetes. We examined the association between IHHSBP and CVD in type 2 diabetes.

MATERIALS AND METHODS: This retrospective cohort study included 1082 individuals with type 2 diabetes, aged 20 to 90 years, without a history of macrovascular complications. Home blood pressure (HBP) was measured three times every morning and evening for 14 days. Cox proportional hazards models were used to examine the relationship between IHHSBP and CVD incidence.

RESULTS: With the normal HBP group as the reference, the adjusted hazard ratio (HR) (95% confidence interval [CI]) for CVD was 1.58 (1.02-2.43) in the IHHSBP group. Correcting for antihypertensive medication use did not change HR. Based on sex, the adjusted HR (95% CI) for CVD was 1.25 (0.74-2.13) in males and 2.28 (1.01-5.15) in females.

CONCLUSIONS: In individuals with type 2 diabetes, those with IHHSBP had a higher HR for cardiovascular disease than those with normal HBP. But, Isolated high home diastolic blood pressure and high HBP were not. The association between IHHSBP and CVD was stronger in females than in males.

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - volume:20

Enthalten in:

Diabetes & vascular disease research - 20(2023), 6 vom: 08. Nov., Seite 14791641231221264

Sprache:

Englisch

Beteiligte Personen:

Hosomi, Yukako [VerfasserIn]
Ushigome, Emi [VerfasserIn]
Kitagawa, Nobuko [VerfasserIn]
Kitagawa, Noriyuki [VerfasserIn]
Tanaka, Toru [VerfasserIn]
Hasegawa, Goji [VerfasserIn]
Ohnishi, Masayoshi [VerfasserIn]
Tsunoda, Sei [VerfasserIn]
Ushigome, Hidetaka [VerfasserIn]
Nakamura, Naoto [VerfasserIn]
Asano, Mai [VerfasserIn]
Hamaguchi, Masahide [VerfasserIn]
Yamazaki, Masahiro [VerfasserIn]
Fukui, Michiaki [VerfasserIn]

Links:

Volltext

Themen:

Cardiovascular diseases
Diabetes mellitus
Home blood pressure measurement
Isolated high home systolic blood pressure
Journal Article
KAMOGAWA-HBP study
Multicenter study
Type 2

Anmerkungen:

Date Revised 08.12.2023

published: Print

Citation Status In-Process

doi:

10.1177/14791641231221264

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM365543160