COVID-19 breakthrough infections in type 1 diabetes mellitus : a cross-sectional study by the COVID-19 Vaccination in Autoimmune Diseases (COVAD) Group
© 2023. The Author(s)..
To investigate the frequency, profile, and severity of COVID-19 breakthrough infections (BI) in patients with type I diabetes mellitus (T1DM) compared to healthy controls (HC) after vaccination. The second COVID-19 Vaccination in Autoimmune Diseases (COVAD-2) survey is a multinational cross-sectional electronic survey which has collected data on patients suffering from various autoimmune diseases including T1DM. We performed a subgroup analysis on this cohort to investigate COVID-19 BI characteristics in patients with T1DM. Logistic regression with propensity score matching analysis was performed. A total of 9595 individuals were included in the analysis, with 100 patients having T1DM. Among the fully vaccinated cohort, 16 (16%) T1DM patients had one BI and 2 (2%) had two BIs. No morbidities or deaths were reported, except for one patient who required hospitalization with oxygen without admission to intensive care. The frequency, clinical features, and severity of BIs were not significantly different between T1DM patients and HCs after adjustment for confounding factors. Our study did not show any statistically significant differences in the frequency, symptoms, duration, or critical care requirements between T1DM and HCs after COVID-19 vaccination. Further research is needed to identify factors associated with inadequate vaccine response in patients with BIs, especially in patients with autoimmune diseases.
Medienart: |
E-Artikel |
---|
Erscheinungsjahr: |
2024 |
---|---|
Erschienen: |
2024 |
Enthalten in: |
Zur Gesamtaufnahme - volume:44 |
---|---|
Enthalten in: |
Rheumatology international - 44(2024), 1 vom: 27. Jan., Seite 73-80 |
Sprache: |
Englisch |
---|
Beteiligte Personen: |
Panchawagh, Suhrud [VerfasserIn] |
---|
Links: |
---|
Themen: |
Breakthrough infections |
---|
Anmerkungen: |
Date Completed 08.01.2024 Date Revised 20.03.2024 published: Print-Electronic Citation Status MEDLINE |
---|
doi: |
10.1007/s00296-023-05496-y |
---|
funding: |
|
---|---|
Förderinstitution / Projekttitel: |
|
PPN (Katalog-ID): |
NLM365509043 |
---|
LEADER | 01000caa a22002652 4500 | ||
---|---|---|---|
001 | NLM365509043 | ||
003 | DE-627 | ||
005 | 20240320233738.0 | ||
007 | cr uuu---uuuuu | ||
008 | 231226s2024 xx |||||o 00| ||eng c | ||
024 | 7 | |a 10.1007/s00296-023-05496-y |2 doi | |
028 | 5 | 2 | |a pubmed24n1337.xml |
035 | |a (DE-627)NLM365509043 | ||
035 | |a (NLM)38060005 | ||
040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
041 | |a eng | ||
100 | 1 | |a Panchawagh, Suhrud |e verfasserin |4 aut | |
245 | 1 | 0 | |a COVID-19 breakthrough infections in type 1 diabetes mellitus |b a cross-sectional study by the COVID-19 Vaccination in Autoimmune Diseases (COVAD) Group |
264 | 1 | |c 2024 | |
336 | |a Text |b txt |2 rdacontent | ||
337 | |a ƒaComputermedien |b c |2 rdamedia | ||
338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
500 | |a Date Completed 08.01.2024 | ||
500 | |a Date Revised 20.03.2024 | ||
500 | |a published: Print-Electronic | ||
500 | |a Citation Status MEDLINE | ||
520 | |a © 2023. The Author(s). | ||
520 | |a To investigate the frequency, profile, and severity of COVID-19 breakthrough infections (BI) in patients with type I diabetes mellitus (T1DM) compared to healthy controls (HC) after vaccination. The second COVID-19 Vaccination in Autoimmune Diseases (COVAD-2) survey is a multinational cross-sectional electronic survey which has collected data on patients suffering from various autoimmune diseases including T1DM. We performed a subgroup analysis on this cohort to investigate COVID-19 BI characteristics in patients with T1DM. Logistic regression with propensity score matching analysis was performed. A total of 9595 individuals were included in the analysis, with 100 patients having T1DM. Among the fully vaccinated cohort, 16 (16%) T1DM patients had one BI and 2 (2%) had two BIs. No morbidities or deaths were reported, except for one patient who required hospitalization with oxygen without admission to intensive care. The frequency, clinical features, and severity of BIs were not significantly different between T1DM patients and HCs after adjustment for confounding factors. Our study did not show any statistically significant differences in the frequency, symptoms, duration, or critical care requirements between T1DM and HCs after COVID-19 vaccination. Further research is needed to identify factors associated with inadequate vaccine response in patients with BIs, especially in patients with autoimmune diseases | ||
650 | 4 | |a Journal Article | |
650 | 4 | |a Breakthrough infections | |
650 | 4 | |a COVID-19 | |
650 | 4 | |a Survey | |
650 | 4 | |a Type 1 diabetes mellitus | |
650 | 4 | |a Vaccine | |
650 | 7 | |a COVID-19 Vaccines |2 NLM | |
700 | 1 | |a Ravichandran, Naveen |e verfasserin |4 aut | |
700 | 1 | |a Barman, Bhupen |e verfasserin |4 aut | |
700 | 1 | |a Nune, Arvind |e verfasserin |4 aut | |
700 | 1 | |a Javaid, Mahnoor |e verfasserin |4 aut | |
700 | 1 | |a Gracia-Ramos, Abraham Edgar |e verfasserin |4 aut | |
700 | 1 | |a Day, Jessica |e verfasserin |4 aut | |
700 | 1 | |a Joshi, Mrudula |e verfasserin |4 aut | |
700 | 1 | |a Kuwana, Masataka |e verfasserin |4 aut | |
700 | 1 | |a Saha, Sreoshy |e verfasserin |4 aut | |
700 | 1 | |a Pande, Arunkumar R |e verfasserin |4 aut | |
700 | 1 | |a Caballero-Uribe, Carlo Vinicio |e verfasserin |4 aut | |
700 | 1 | |a Velikova, Tsvetelina |e verfasserin |4 aut | |
700 | 1 | |a Parodis, Ioannis |e verfasserin |4 aut | |
700 | 1 | |a Knitza, Johannes |e verfasserin |4 aut | |
700 | 1 | |a Kadam, Esha |e verfasserin |4 aut | |
700 | 1 | |a Tan, Ai Lyn |e verfasserin |4 aut | |
700 | 1 | |a Shinjo, Samuel Katsuyuki |e verfasserin |4 aut | |
700 | 1 | |a Boro, Hiya |e verfasserin |4 aut | |
700 | 0 | |a COVAD Study Group |e verfasserin |4 aut | |
700 | 1 | |a Aggarwal, Rohit |e verfasserin |4 aut | |
700 | 1 | |a Agarwal, Vikas |e verfasserin |4 aut | |
700 | 1 | |a Chatterjee, Tulika |e verfasserin |4 aut | |
700 | 1 | |a Gupta, Latika |e verfasserin |4 aut | |
700 | 1 | |a Sen, Parikshit |e investigator |4 oth | |
700 | 1 | |a Day, Jessica |e investigator |4 oth | |
700 | 1 | |a Nikiphorou, Elena |e investigator |4 oth | |
700 | 1 | |a Ziade, Nelly |e investigator |4 oth | |
700 | 1 | |a Milchert, Marcin |e investigator |4 oth | |
700 | 1 | |a Cavagna, Lorenzo |e investigator |4 oth | |
700 | 1 | |a Chen, Yi Ming |e investigator |4 oth | |
700 | 1 | |a Makol, Ashima |e investigator |4 oth | |
700 | 1 | |a Agarwal, Vishwesh |e investigator |4 oth | |
700 | 1 | |a Patel, Aarat |e investigator |4 oth | |
700 | 1 | |a Pauling, John D |e investigator |4 oth | |
700 | 1 | |a Wincup, Chris |e investigator |4 oth | |
700 | 1 | |a Tehozol, Erick Adrian Zamora |e investigator |4 oth | |
700 | 1 | |a Serrano, Jorge Rojas |e investigator |4 oth | |
700 | 1 | |a La Torre, Ignacia García-De |e investigator |4 oth | |
700 | 1 | |a Colunga-Pedraza, Iris J |e investigator |4 oth | |
700 | 1 | |a Merayo-Chalico, Javier |e investigator |4 oth | |
700 | 1 | |a Chibuzo, Okwara Celestine |e investigator |4 oth | |
700 | 1 | |a Katchamart, Wanruchada |e investigator |4 oth | |
700 | 1 | |a Goo, Phonpen Akawatcharangura |e investigator |4 oth | |
700 | 1 | |a Shumnalieva, Russka |e investigator |4 oth | |
700 | 1 | |a Hoff, Leonardo Santos |e investigator |4 oth | |
700 | 1 | |a El Kibbi, Lina |e investigator |4 oth | |
700 | 1 | |a Halabi, Hussein |e investigator |4 oth | |
700 | 1 | |a Vaidya, Binit |e investigator |4 oth | |
700 | 1 | |a Shaharir, Syahrul Sazliyana |e investigator |4 oth | |
700 | 1 | |a Hasan, ATMTanveer |e investigator |4 oth | |
700 | 1 | |a Dey, Dzifa |e investigator |4 oth | |
700 | 1 | |a Gutiérrez, Carlos Enrique Toro |e investigator |4 oth | |
700 | 1 | |a Lilleker, James B |e investigator |4 oth | |
700 | 1 | |a Salim, Babur |e investigator |4 oth | |
700 | 1 | |a Gheita, Tamer |e investigator |4 oth | |
700 | 1 | |a Distler, Oliver |e investigator |4 oth | |
700 | 1 | |a Saavedra, Miguel A |e investigator |4 oth | |
700 | 1 | |a Kardes, Sinan |e investigator |4 oth | |
700 | 1 | |a Andreoli, Laura |e investigator |4 oth | |
700 | 1 | |a Lini, Daniele |e investigator |4 oth | |
700 | 1 | |a Schreiber, Karen |e investigator |4 oth | |
700 | 1 | |a Vince, Melinda Nagy |e investigator |4 oth | |
700 | 1 | |a Singh, Yogesh Preet |e investigator |4 oth | |
700 | 1 | |a Ranjan, Rajiv |e investigator |4 oth | |
700 | 1 | |a Jain, Avinash |e investigator |4 oth | |
700 | 1 | |a Pandya, Sapan C |e investigator |4 oth | |
700 | 1 | |a Pilania, Rakesh Kumar |e investigator |4 oth | |
700 | 1 | |a Sharma, Aman |e investigator |4 oth | |
700 | 1 | |a M, Manesh Manoj |e investigator |4 oth | |
700 | 1 | |a Gupta, Vikas |e investigator |4 oth | |
700 | 1 | |a Kavadichanda, Chengappa G |e investigator |4 oth | |
700 | 1 | |a Patro, Pradeepta Sekhar |e investigator |4 oth | |
700 | 1 | |a Ajmani, Sajal |e investigator |4 oth | |
700 | 1 | |a Phatak, Sanat |e investigator |4 oth | |
700 | 1 | |a Goswami, Rudra Prosad |e investigator |4 oth | |
700 | 1 | |a Chowdhury, Abhra Chandra |e investigator |4 oth | |
700 | 1 | |a Mathew, Ashish Jacob |e investigator |4 oth | |
700 | 1 | |a Shenoy, Padnamabha |e investigator |4 oth | |
700 | 1 | |a Asranna, Ajay |e investigator |4 oth | |
700 | 1 | |a Bommakanti, Keerthi Talari |e investigator |4 oth | |
700 | 1 | |a Shukla, Anuj |e investigator |4 oth | |
700 | 1 | |a Pande, Arunkumar R |e investigator |4 oth | |
700 | 1 | |a Chandwar, Kunal |e investigator |4 oth | |
700 | 1 | |a Ghodke, Akanksha |e investigator |4 oth | |
700 | 1 | |a Fazal, Zoha Zahid |e investigator |4 oth | |
700 | 1 | |a Cansu, Döndü Üsküdar |e investigator |4 oth | |
700 | 1 | |a Yıldırım, Reşit |e investigator |4 oth | |
700 | 1 | |a Gasparyan, Armen Yuri |e investigator |4 oth | |
700 | 1 | |a Del Papa, Nicoletta |e investigator |4 oth | |
700 | 1 | |a Sambataro, Gianluca |e investigator |4 oth | |
700 | 1 | |a Fabiola, Atzeni |e investigator |4 oth | |
700 | 1 | |a Govoni, Marcello |e investigator |4 oth | |
700 | 1 | |a Parisi, Simone |e investigator |4 oth | |
700 | 1 | |a Bocci, Elena Bartoloni |e investigator |4 oth | |
700 | 1 | |a Sebastiani, Gian Domenico |e investigator |4 oth | |
700 | 1 | |a Fusaro, Enrico |e investigator |4 oth | |
700 | 1 | |a Sebastiani, Marco |e investigator |4 oth | |
700 | 1 | |a Quartuccio, Luca |e investigator |4 oth | |
700 | 1 | |a Franceschini, Franco |e investigator |4 oth | |
700 | 1 | |a Sainaghi, Pier Paolo |e investigator |4 oth | |
700 | 1 | |a Orsolini, Giovanni |e investigator |4 oth | |
700 | 1 | |a De Angelis, Rossella |e investigator |4 oth | |
700 | 1 | |a Danielli, Maria Giovanna |e investigator |4 oth | |
700 | 1 | |a Venerito, Vincenzo |e investigator |4 oth | |
700 | 1 | |a Grignaschi, Silvia |e investigator |4 oth | |
700 | 1 | |a Giollo, Alessandro |e investigator |4 oth | |
700 | 1 | |a Alluno, Alessia |e investigator |4 oth | |
700 | 1 | |a Ioannone, Florenzo |e investigator |4 oth | |
700 | 1 | |a Fornaro, Marco |e investigator |4 oth | |
700 | 1 | |a Traboco, Lisa S |e investigator |4 oth | |
700 | 1 | |a Wibowo, Suryo Anggoro Kusumo |e investigator |4 oth | |
700 | 1 | |a Loarce-Martos, Jesús |e investigator |4 oth | |
700 | 1 | |a Prieto-González, Sergio |e investigator |4 oth | |
700 | 1 | |a Gonzalez, Raquel Aranega |e investigator |4 oth | |
700 | 1 | |a Yoshida, Akira |e investigator |4 oth | |
700 | 1 | |a Nakashima, Ran |e investigator |4 oth | |
700 | 1 | |a Sato, Shinji |e investigator |4 oth | |
700 | 1 | |a Kimura, Naoki |e investigator |4 oth | |
700 | 1 | |a Kaneko, Yuko |e investigator |4 oth | |
700 | 1 | |a Gono, Takahisa |e investigator |4 oth | |
700 | 1 | |a Tomaras, Stylianos |e investigator |4 oth | |
700 | 1 | |a Proft, Fabian Nikolai |e investigator |4 oth | |
700 | 1 | |a Holzer, Marie-Therese |e investigator |4 oth | |
773 | 0 | 8 | |i Enthalten in |t Rheumatology international |d 1985 |g 44(2024), 1 vom: 27. Jan., Seite 73-80 |w (DE-627)NLM012644315 |x 1437-160X |7 nnns |
773 | 1 | 8 | |g volume:44 |g year:2024 |g number:1 |g day:27 |g month:01 |g pages:73-80 |
856 | 4 | 0 | |u http://dx.doi.org/10.1007/s00296-023-05496-y |3 Volltext |
912 | |a GBV_USEFLAG_A | ||
912 | |a GBV_NLM | ||
951 | |a AR | ||
952 | |d 44 |j 2024 |e 1 |b 27 |c 01 |h 73-80 |