The "autoimmune/inflammatory syndrome induced by adjuvants" (ASIA) after COVID-19 infection : A case report
Copyright © 2023 Elsevier España, S.L.U. and Sociedad Española de Reumatología y Colegio Mexicano de Reumatología. All rights reserved..
The term "autoimmune/inflammatory syndrome induced by adjuvants" (ASIA) describes a variety of autoimmune conditions triggered by exposure to substances with adjuvant activity. We present the case of a patient with a history of biopolymer infiltration in both glutes, who years later experienced progressive weakness and pain in the lower limbs, myalgias, cramps, and progressive functional impotence following a mild COVID-19 infection. Laboratory test results were not consistent with any autoimmune disease. Physical examination revealed diffuse bilateral subcutaneous nodules. After an extensive etiological study, a gluteal biopsy was performed, which showed findings compatible with sclerosing lipogranuloma. Our patient required treatment with high-dose glucocorticoids and showed significant improvement in symptoms during long-term follow-up. We suggest the role of COVID-19 infection as a possible trigger for ASIA, as it has already been described as a trigger for several other autoimmune diseases.
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2023 |
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Erschienen: |
2023 |
Enthalten in: |
Zur Gesamtaufnahme - volume:19 |
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Enthalten in: |
Reumatologia clinica - 19(2023), 10 vom: 06. Dez., Seite 593-595 |
Sprache: |
Englisch |
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Beteiligte Personen: |
Aguilera-Fernandez, Patricia [VerfasserIn] |
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Links: |
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Anmerkungen: |
Date Completed 11.12.2023 Date Revised 11.12.2023 published: Print Citation Status MEDLINE |
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doi: |
10.1016/j.reumae.2023.09.002 |
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funding: |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM365478911 |
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520 | |a Copyright © 2023 Elsevier España, S.L.U. and Sociedad Española de Reumatología y Colegio Mexicano de Reumatología. All rights reserved. | ||
520 | |a The term "autoimmune/inflammatory syndrome induced by adjuvants" (ASIA) describes a variety of autoimmune conditions triggered by exposure to substances with adjuvant activity. We present the case of a patient with a history of biopolymer infiltration in both glutes, who years later experienced progressive weakness and pain in the lower limbs, myalgias, cramps, and progressive functional impotence following a mild COVID-19 infection. Laboratory test results were not consistent with any autoimmune disease. Physical examination revealed diffuse bilateral subcutaneous nodules. After an extensive etiological study, a gluteal biopsy was performed, which showed findings compatible with sclerosing lipogranuloma. Our patient required treatment with high-dose glucocorticoids and showed significant improvement in symptoms during long-term follow-up. We suggest the role of COVID-19 infection as a possible trigger for ASIA, as it has already been described as a trigger for several other autoimmune diseases | ||
650 | 4 | |a Case Reports | |
650 | 4 | |a ASIA | |
650 | 4 | |a Autoimmune/inflammatory syndrome induced by adjuvants | |
650 | 4 | |a COVID-19 | |
650 | 4 | |a Gluteal implants | |
650 | 4 | |a Implantes glúteos | |
650 | 4 | |a Lipogranuloma esclerosante | |
650 | 4 | |a Sclerosing lipogranuloma | |
650 | 4 | |a Síndrome autoinmune/inflamatorio inducido por adyuvantes | |
650 | 7 | |a Adjuvants, Immunologic |2 NLM | |
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700 | 1 | |a Parra Parente, Tamara |e verfasserin |4 aut | |
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