The "autoimmune/inflammatory syndrome induced by adjuvants" (ASIA) after COVID-19 infection : A case report

Copyright © 2023 Elsevier España, S.L.U. and Sociedad Española de Reumatología y Colegio Mexicano de Reumatología. All rights reserved..

The term "autoimmune/inflammatory syndrome induced by adjuvants" (ASIA) describes a variety of autoimmune conditions triggered by exposure to substances with adjuvant activity. We present the case of a patient with a history of biopolymer infiltration in both glutes, who years later experienced progressive weakness and pain in the lower limbs, myalgias, cramps, and progressive functional impotence following a mild COVID-19 infection. Laboratory test results were not consistent with any autoimmune disease. Physical examination revealed diffuse bilateral subcutaneous nodules. After an extensive etiological study, a gluteal biopsy was performed, which showed findings compatible with sclerosing lipogranuloma. Our patient required treatment with high-dose glucocorticoids and showed significant improvement in symptoms during long-term follow-up. We suggest the role of COVID-19 infection as a possible trigger for ASIA, as it has already been described as a trigger for several other autoimmune diseases.

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - volume:19

Enthalten in:

Reumatologia clinica - 19(2023), 10 vom: 06. Dez., Seite 593-595

Sprache:

Englisch

Beteiligte Personen:

Aguilera-Fernandez, Patricia [VerfasserIn]
Navarro-Saez, María Del Carmen [VerfasserIn]
Feijoo-Massó, Carlos [VerfasserIn]
Esteve-Valverde, Enrique [VerfasserIn]
Calzado Isbert, Sonia [VerfasserIn]
Parra Parente, Tamara [VerfasserIn]

Links:

Volltext

Themen:

ASIA
Adjuvants, Immunologic
Autoimmune/inflammatory syndrome induced by adjuvants
COVID-19
Case Reports
Gluteal implants
Implantes glúteos
Lipogranuloma esclerosante
Síndrome autoinmune/inflamatorio inducido por adyuvantes
Sclerosing lipogranuloma

Anmerkungen:

Date Completed 11.12.2023

Date Revised 11.12.2023

published: Print

Citation Status MEDLINE

doi:

10.1016/j.reumae.2023.09.002

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM365478911