Production of pharmaceutical grade [201Tl]Thallous chloride using 30 MeV cyclotron

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Multiple patient doses of [201Tl]TlCl has been produced using electrodeposited enriched 203Tl in 30 MeV cyclotron (Cyclone-30) with 28 MeV proton energy at 50 μA beam current for 8 h. Ion Exchange Column Chromatography (IECC) and liquid-liquid extraction has been employed for semi-automated radiochemical separation and purification of produced [201Tl]TlCl. The produced [201Tl]TlCl was used in coronary artery disease (CAD) patients.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:204

Enthalten in:

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine - 204(2024) vom: 08. Jan., Seite 111128

Sprache:

Englisch

Beteiligte Personen:

Chattopadhyay, Sankha [VerfasserIn]
Barua, Luna [VerfasserIn]
Mahesh, D G [VerfasserIn]
Ash, Shayantani [VerfasserIn]
Mitra, Arpit [VerfasserIn]
Saha Das, Sujata [VerfasserIn]
Singha, Samarjit [VerfasserIn]
Alam, Md Neyar [VerfasserIn]
Madhusmita [VerfasserIn]
Roy, Suprakash [VerfasserIn]
Dhang, Prosenjit [VerfasserIn]
Jain, Mukesh [VerfasserIn]

Links:

Volltext

Themen:

(201)Tl]TlCl
30 MeV cyclotron
37CB58V15B
AD84R52XLF
H91Z8HBK1B
Ischemia
Journal Article
Pharmaceutical Preparations
Pharmacopeia
SPECT/CT
Thallium
Thallium chloride
Thallium-201

Anmerkungen:

Date Completed 02.01.2024

Date Revised 02.01.2024

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1016/j.apradiso.2023.111128

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM365471895