CfErp3 regulates growth, conidiation, inducing ipomeamarone and the pathogenicity of Ceratocystis fimbriata
Copyright © 2023 The Authors. Published by Elsevier Inc. All rights reserved..
The Erp3 protein, which is an important member of the p24 family, is primarily responsible for the transport of cargo from the ER to the Golgi apparatus in Saccharomyces cerevisiae. However, the function of Erp3 in plant pathogenic fungi has not been reported. In this study, we characterized the ERP3 gene in Ceratocystis fimbriata, which causes the devastating disease sweetpotato black rot. The ΔCferp3 mutants exhibited slow growth, reduced conidia production, attenuated virulence, and reduced ability to induce host to produce toxins. Further analysis revealed that CfErp3 was localized in the ER and vesicles and regulated endocytosis, cell wall integrity, and osmotic stress responses, modulated ROS levels, and the production of ipomeamarone during pathogen-host interactions. These results indicate that CfErp3 regulates C. fimbriata growth and pathogenicity as well as the production of ipomeamarone in sweetpotato by controlling endocytosis, oxidative homeostasis, and responses to cell wall and osmotic stresses.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:170 |
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| Enthalten in: |
Fungal genetics and biology : FG & B - 170(2024) vom: 15. Feb., Seite 103846 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Li, Changgen [VerfasserIn] |
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| Links: |
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| Themen: |
20007-82-3 |
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| Anmerkungen: |
Date Completed 05.02.2024 Date Revised 05.02.2024 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.fgb.2023.103846 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| 520 | |a Copyright © 2023 The Authors. Published by Elsevier Inc. All rights reserved. | ||
| 520 | |a The Erp3 protein, which is an important member of the p24 family, is primarily responsible for the transport of cargo from the ER to the Golgi apparatus in Saccharomyces cerevisiae. However, the function of Erp3 in plant pathogenic fungi has not been reported. In this study, we characterized the ERP3 gene in Ceratocystis fimbriata, which causes the devastating disease sweetpotato black rot. The ΔCferp3 mutants exhibited slow growth, reduced conidia production, attenuated virulence, and reduced ability to induce host to produce toxins. Further analysis revealed that CfErp3 was localized in the ER and vesicles and regulated endocytosis, cell wall integrity, and osmotic stress responses, modulated ROS levels, and the production of ipomeamarone during pathogen-host interactions. These results indicate that CfErp3 regulates C. fimbriata growth and pathogenicity as well as the production of ipomeamarone in sweetpotato by controlling endocytosis, oxidative homeostasis, and responses to cell wall and osmotic stresses | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Ceratocystis fimbriata | |
| 650 | 4 | |a Erp3 | |
| 650 | 4 | |a Ipomeamarone | |
| 650 | 4 | |a Pathogenicity | |
| 650 | 4 | |a Sweetpotato black rot | |
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| 700 | 1 | |a Cong, Hao |e verfasserin |4 aut | |
| 700 | 1 | |a Cao, Xiaoying |e verfasserin |4 aut | |
| 700 | 1 | |a Sun, Yong |e verfasserin |4 aut | |
| 700 | 1 | |a Lu, Kailun |e verfasserin |4 aut | |
| 700 | 1 | |a Li, Ludan |e verfasserin |4 aut | |
| 700 | 1 | |a Wang, Yiming |e verfasserin |4 aut | |
| 700 | 1 | |a Zhang, Yongjing |e verfasserin |4 aut | |
| 700 | 1 | |a Li, Qiang |e verfasserin |4 aut | |
| 700 | 1 | |a Jiang, Jihong |e verfasserin |4 aut | |
| 700 | 1 | |a Li, Lianwei |e verfasserin |4 aut | |
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