The role of lncRNAs in intermittent hypoxia and sleep Apnea : A review of experimental and clinical evidence
Copyright © 2023 Elsevier B.V. All rights reserved..
In this narrative review, we present a comprehensive assessment on the putative roles of long non-coding RNAs (lncRNAs) in intermittent hypoxia (IH) and sleep apnea. Collectively, the evidence from cell culture, animal, and clinical research studies points to the functional involvement of lncRNAs in the pathogenesis, diagnosis, and potential treatment strategies for this highly prevalent disorder. Further research is clearly warranted to uncover the mechanistic pathways and to exploit the therapeutic potential of lncRNAs, thereby improving the management and outcomes of patients suffering from sleep apnea.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:113 |
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| Enthalten in: |
Sleep medicine - 113(2024) vom: 02. Jan., Seite 188-197 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Moradi, Mohammad-Taher [VerfasserIn] |
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| Links: |
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| Themen: |
CeRNA |
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| Anmerkungen: |
Date Completed 08.01.2024 Date Revised 16.01.2024 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.sleep.2023.11.014 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM365343161 |
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| 245 | 1 | 4 | |a The role of lncRNAs in intermittent hypoxia and sleep Apnea |b A review of experimental and clinical evidence |
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| 500 | |a Date Revised 16.01.2024 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2023 Elsevier B.V. All rights reserved. | ||
| 520 | |a In this narrative review, we present a comprehensive assessment on the putative roles of long non-coding RNAs (lncRNAs) in intermittent hypoxia (IH) and sleep apnea. Collectively, the evidence from cell culture, animal, and clinical research studies points to the functional involvement of lncRNAs in the pathogenesis, diagnosis, and potential treatment strategies for this highly prevalent disorder. Further research is clearly warranted to uncover the mechanistic pathways and to exploit the therapeutic potential of lncRNAs, thereby improving the management and outcomes of patients suffering from sleep apnea | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Review | |
| 650 | 4 | |a HIF | |
| 650 | 4 | |a Long non-coding RNA (lncRNA) | |
| 650 | 4 | |a Sleep apnea | |
| 650 | 4 | |a ceRNA | |
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| 700 | 1 | |a Sharafkhaneh, Amir |e verfasserin |4 aut | |
| 700 | 1 | |a Khazaie, Habibolah |e verfasserin |4 aut | |
| 700 | 1 | |a Gozal, David |e verfasserin |4 aut | |
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