Sleep quality and associated factors among patients with chronic kidney disease in Nigeria : a cross-sectional study
© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ..
OBJECTIVE: Poor sleep quality adversely affects the overall well-being and outcomes of patients with chronic kidney disease (CKD). However, it has not been well studied in Africans with CKD. We determined the prevalence of poor sleep quality and associated factors among patients with CKD.
DESIGN: This was a cross-sectional study that involved patients with CKD.
SETTINGS: The study was carried out in the outpatient clinic of nine hospitals in Nigeria.
METHODS: Sleep quality, depressive and anxiety symptoms and quality of life (QoL) were assessed among 307 patients with CKD using Pittsburgh Sleep Quality Index Questionnaire, Hospital Anxiety Depression Scale Questionnaire and 12-item Short Form Health Survey Quality of Life Questionnaire, respectively. The prevalence of poor sleep quality and associated factors were determined. A p<0.05 was considered as statistically significant.
RESULTS: The mean age of the study participants was 51.40±15.17 years. The male:female ratio was 1.5:1 One hundred and twenty-one (39.4%) of the patients were on maintenance haemodialysis (MHD). The prevalence of poor sleep quality, anxiety symptoms and depressive symptoms among the patients was 50.2%, 37.8% and 17.6%, respectively. The prevalence of poor sleep quality in the CKD stages 3, 4, 5 and 5D was 38.1%, 42.6%, 52.2% and 58.7%, respectively. The prevalence of poor sleep quality was significantly higher in MHD patients compared with predialysis CKD (59.5% vs 43.6%; p=0.008). Factors associated with poor sleep quality were CKD stage (p=0.035), anaemia (p=0.003), pruritus (p=0.045), anxiety symptoms (p≤0.001), depressive symptoms (p≤0.001) and reduced QoL (p≤0.001). On multivariate analysis, factors associated with poor sleep were anxiety (AOR 2.19; 95% CI 1.27 to 3.79; p=0.005), anaemia (AOR 5.49; 95% CI 1.43 to 21.00;p=0.013) and reduced physical component of QoL (AOR 4.11; 95% CI 1.61 to 10.47; p=0.003).
CONCLUSION: Poor sleep quality is common among patients with CKD especially in the advanced stage. The significant factors associated with poor sleep quality were QoL, anaemia and anxiety symptoms. These factors should be adequately managed to improve the overall outcomes of patients with CKD.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2023 |
|---|---|
| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:13 |
|---|---|
| Enthalten in: |
BMJ open - 13(2023), 12 vom: 01. Dez., Seite e074025 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Adejumo, Oluseyi Ademola [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Chronic renal failure |
|---|
| Anmerkungen: |
Date Completed 04.12.2023 Date Revised 24.01.2024 published: Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1136/bmjopen-2023-074025 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM365314218 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM365314218 | ||
| 003 | DE-627 | ||
| 005 | 20240124232008.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231226s2023 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1136/bmjopen-2023-074025 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1269.xml |
| 035 | |a (DE-627)NLM365314218 | ||
| 035 | |a (NLM)38040427 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Adejumo, Oluseyi Ademola |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Sleep quality and associated factors among patients with chronic kidney disease in Nigeria |b a cross-sectional study |
| 264 | 1 | |c 2023 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 04.12.2023 | ||
| 500 | |a Date Revised 24.01.2024 | ||
| 500 | |a published: Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. | ||
| 520 | |a OBJECTIVE: Poor sleep quality adversely affects the overall well-being and outcomes of patients with chronic kidney disease (CKD). However, it has not been well studied in Africans with CKD. We determined the prevalence of poor sleep quality and associated factors among patients with CKD | ||
| 520 | |a DESIGN: This was a cross-sectional study that involved patients with CKD | ||
| 520 | |a SETTINGS: The study was carried out in the outpatient clinic of nine hospitals in Nigeria | ||
| 520 | |a METHODS: Sleep quality, depressive and anxiety symptoms and quality of life (QoL) were assessed among 307 patients with CKD using Pittsburgh Sleep Quality Index Questionnaire, Hospital Anxiety Depression Scale Questionnaire and 12-item Short Form Health Survey Quality of Life Questionnaire, respectively. The prevalence of poor sleep quality and associated factors were determined. A p<0.05 was considered as statistically significant | ||
| 520 | |a RESULTS: The mean age of the study participants was 51.40±15.17 years. The male:female ratio was 1.5:1 One hundred and twenty-one (39.4%) of the patients were on maintenance haemodialysis (MHD). The prevalence of poor sleep quality, anxiety symptoms and depressive symptoms among the patients was 50.2%, 37.8% and 17.6%, respectively. The prevalence of poor sleep quality in the CKD stages 3, 4, 5 and 5D was 38.1%, 42.6%, 52.2% and 58.7%, respectively. The prevalence of poor sleep quality was significantly higher in MHD patients compared with predialysis CKD (59.5% vs 43.6%; p=0.008). Factors associated with poor sleep quality were CKD stage (p=0.035), anaemia (p=0.003), pruritus (p=0.045), anxiety symptoms (p≤0.001), depressive symptoms (p≤0.001) and reduced QoL (p≤0.001). On multivariate analysis, factors associated with poor sleep were anxiety (AOR 2.19; 95% CI 1.27 to 3.79; p=0.005), anaemia (AOR 5.49; 95% CI 1.43 to 21.00;p=0.013) and reduced physical component of QoL (AOR 4.11; 95% CI 1.61 to 10.47; p=0.003) | ||
| 520 | |a CONCLUSION: Poor sleep quality is common among patients with CKD especially in the advanced stage. The significant factors associated with poor sleep quality were QoL, anaemia and anxiety symptoms. These factors should be adequately managed to improve the overall outcomes of patients with CKD | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Chronic renal failure | |
| 650 | 4 | |a Quality of Life | |
| 650 | 4 | |a Sleep medicine | |
| 700 | 1 | |a Edeki, Imuetinyan Rashida |e verfasserin |4 aut | |
| 700 | 1 | |a Mamven, Manmak |e verfasserin |4 aut | |
| 700 | 1 | |a Oguntola, Olawale Stephen |e verfasserin |4 aut | |
| 700 | 1 | |a Okoye, Ogochukwu Chinedum |e verfasserin |4 aut | |
| 700 | 1 | |a Akinbodewa, Akinwumi Ayodeji |e verfasserin |4 aut | |
| 700 | 1 | |a Okaka, Enajite Ibiene |e verfasserin |4 aut | |
| 700 | 1 | |a Ahmed, Sulaiman Dazumi |e verfasserin |4 aut | |
| 700 | 1 | |a Egbi, Oghenekaro Gódwin |e verfasserin |4 aut | |
| 700 | 1 | |a Falade, Joshua |e verfasserin |4 aut | |
| 700 | 1 | |a Dada, Samuel Ayokunle |e verfasserin |4 aut | |
| 700 | 1 | |a Ogiator, Monday Ogiagah |e verfasserin |4 aut | |
| 700 | 1 | |a Okoh, Barbara |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t BMJ open |d 2012 |g 13(2023), 12 vom: 01. Dez., Seite e074025 |w (DE-627)NLM215724372 |x 2044-6055 |7 nnns |
| 773 | 1 | 8 | |g volume:13 |g year:2023 |g number:12 |g day:01 |g month:12 |g pages:e074025 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1136/bmjopen-2023-074025 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 13 |j 2023 |e 12 |b 01 |c 12 |h e074025 | ||