Metabolic Control of Cardiomyocyte Cell Cycle
Copyright: © 2023 The Author(s)..
Current therapies for heart failure aim to prevent the deleterious remodeling that occurs after MI injury, but currently no therapies are available to replace lost cardiomyocytes. Several organisms now being studied are capable of regenerating their myocardium by the proliferation of existing cardiomyocytes. In this review, we summarize the main metabolic pathways of the mammalian heart and how modulation of these metabolic pathways through genetic and pharmacological approaches influences cardiomyocyte proliferation and heart regeneration.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:19 |
|---|---|
| Enthalten in: |
Methodist DeBakey cardiovascular journal - 19(2023), 5 vom: 15., Seite 26-36 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Menendez-Montes, Ivan [VerfasserIn] |
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| Links: |
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| Themen: |
Cardiac regeneration |
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| Anmerkungen: |
Date Completed 01.12.2023 Date Revised 30.01.2024 published: Electronic-eCollection Citation Status MEDLINE |
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| doi: |
10.14797/mdcvj.1309 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| 520 | |a Current therapies for heart failure aim to prevent the deleterious remodeling that occurs after MI injury, but currently no therapies are available to replace lost cardiomyocytes. Several organisms now being studied are capable of regenerating their myocardium by the proliferation of existing cardiomyocytes. In this review, we summarize the main metabolic pathways of the mammalian heart and how modulation of these metabolic pathways through genetic and pharmacological approaches influences cardiomyocyte proliferation and heart regeneration | ||
| 650 | 4 | |a Journal Article | |
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