Immune checkpoint inhibitor-induced lichenoid drug eruption-sparing scar burns

© 2023 The Authors. Australasian Journal of Dermatology published by John Wiley & Sons Australia, Ltd on behalf of Australasian College of Dermatologists..

The authors present a striking case of a patient experiencing a lichenoid drug eruption secondary to immunotherapy, curiously sparing scarred skin from past burns. We observed vastly higher amounts of inflammatory lymphoid cells staining for PD-1; 70% in skin with a lichenoid drug reaction and 50% in scarred skin. The lack of a lichenoid reaction at sites of scarred skin may indicate that a basement membrane component may be causative for a lichenoid drug eruption.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:65

Enthalten in:

The Australasian journal of dermatology - 65(2024), 2 vom: 30. März, Seite 163-166

Sprache:

Englisch

Beteiligte Personen:

Truong, Kelvin [VerfasserIn]
Chamberlin, Charmaine Vanessa [VerfasserIn]
Kim, Jennifer [VerfasserIn]
Carlino, Matteo S [VerfasserIn]
Araujo, Raquel Ruiz [VerfasserIn]

Links:

Volltext

Themen:

Case Reports
Immune Checkpoint Inhibitors
Immune-related adverse events
Immunotherapy
Journal Article
Lichenoid eruption
Melanoma
PD-1 inhibitor

Anmerkungen:

Date Completed 11.03.2024

Date Revised 11.03.2024

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1111/ajd.14192

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM365010804