A Literature Review Focusing on the Antiviral Activity of [1,2,4] and [1,2,3]-triazoles
Copyright© Bentham Science Publishers; For any queries, please email at epubbenthamscience.net..
Out of a variety of heterocycles, triazole scaffolds have been shown to play a significant part in a wide array of biological functions. Many drug compounds containing a triazole moiety with important antimicrobial, anticancer and antidepressant properties have been commercialized. In addition, the triazole scaffold exhibits remarkable antiviral activity either incorporated into nucleoside analogs or non-nucleosides. Many synthetic techniques have been produced by scientists around the world as a result of their wide-ranging biological function. In this review, we have tried to summarize new synthetic methods produced by diverse research groups as well as provide a comprehensive description of the function of [1,2,4] and [1,2,3]-triazole derivatives as antiviral agents. Antiviral triazole compounds have been shown to target a wide variety of molecular proteins. In addition, several strains of viruses, including the human immunodeficiency virus, SARS virus, hepatitis B and C viruses, influenza virus, Hantavirus, and herpes virus, were discovered to be susceptible to triazole derivatives. This review article covered the reports for antiviral activity of both 1,2,3- and 1,2,4-triazole moieties up to 2022.
Medienart: |
E-Artikel |
---|
Erscheinungsjahr: |
2023 |
---|---|
Erschienen: |
2023 |
Enthalten in: |
Zur Gesamtaufnahme - year:2023 |
---|---|
Enthalten in: |
Mini reviews in medicinal chemistry - (2023) vom: 24. Nov. |
Sprache: |
Englisch |
---|
Beteiligte Personen: |
Farghaly, Thoraya A [VerfasserIn] |
---|
Links: |
---|
Themen: |
1 |
---|
Anmerkungen: |
Date Revised 27.11.2023 published: Print-Electronic Citation Status Publisher |
---|
doi: |
10.2174/0113895575277122231108095511 |
---|
funding: |
|
---|---|
Förderinstitution / Projekttitel: |
|
PPN (Katalog-ID): |
NLM365001481 |
---|
LEADER | 01000naa a22002652 4500 | ||
---|---|---|---|
001 | NLM365001481 | ||
003 | DE-627 | ||
005 | 20231226100741.0 | ||
007 | cr uuu---uuuuu | ||
008 | 231226s2023 xx |||||o 00| ||eng c | ||
024 | 7 | |a 10.2174/0113895575277122231108095511 |2 doi | |
028 | 5 | 2 | |a pubmed24n1216.xml |
035 | |a (DE-627)NLM365001481 | ||
035 | |a (NLM)38008942 | ||
040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
041 | |a eng | ||
100 | 1 | |a Farghaly, Thoraya A |e verfasserin |4 aut | |
245 | 1 | 2 | |a A Literature Review Focusing on the Antiviral Activity of [1,2,4] and [1,2,3]-triazoles |
264 | 1 | |c 2023 | |
336 | |a Text |b txt |2 rdacontent | ||
337 | |a ƒaComputermedien |b c |2 rdamedia | ||
338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
500 | |a Date Revised 27.11.2023 | ||
500 | |a published: Print-Electronic | ||
500 | |a Citation Status Publisher | ||
520 | |a Copyright© Bentham Science Publishers; For any queries, please email at epubbenthamscience.net. | ||
520 | |a Out of a variety of heterocycles, triazole scaffolds have been shown to play a significant part in a wide array of biological functions. Many drug compounds containing a triazole moiety with important antimicrobial, anticancer and antidepressant properties have been commercialized. In addition, the triazole scaffold exhibits remarkable antiviral activity either incorporated into nucleoside analogs or non-nucleosides. Many synthetic techniques have been produced by scientists around the world as a result of their wide-ranging biological function. In this review, we have tried to summarize new synthetic methods produced by diverse research groups as well as provide a comprehensive description of the function of [1,2,4] and [1,2,3]-triazole derivatives as antiviral agents. Antiviral triazole compounds have been shown to target a wide variety of molecular proteins. In addition, several strains of viruses, including the human immunodeficiency virus, SARS virus, hepatitis B and C viruses, influenza virus, Hantavirus, and herpes virus, were discovered to be susceptible to triazole derivatives. This review article covered the reports for antiviral activity of both 1,2,3- and 1,2,4-triazole moieties up to 2022 | ||
650 | 4 | |a Journal Article | |
650 | 4 | |a 1 | |
650 | 4 | |a 2 | |
650 | 4 | |a 3-triazoles | |
650 | 4 | |a 4-triazoles | |
650 | 4 | |a Antiviral activity | |
650 | 4 | |a COVID-19 | |
650 | 4 | |a HCV | |
650 | 4 | |a heterocycles | |
700 | 1 | |a Masaret, Ghada S |e verfasserin |4 aut | |
700 | 1 | |a Riyadh, Sayed M |e verfasserin |4 aut | |
700 | 1 | |a Harras, Marwa F |e verfasserin |4 aut | |
773 | 0 | 8 | |i Enthalten in |t Mini reviews in medicinal chemistry |d 2001 |g (2023) vom: 24. Nov. |w (DE-627)NLM121595404 |x 1875-5607 |7 nnns |
773 | 1 | 8 | |g year:2023 |g day:24 |g month:11 |
856 | 4 | 0 | |u http://dx.doi.org/10.2174/0113895575277122231108095511 |3 Volltext |
912 | |a GBV_USEFLAG_A | ||
912 | |a GBV_NLM | ||
951 | |a AR | ||
952 | |j 2023 |b 24 |c 11 |