A Case of Lymphangioleiomyomatosis Showing the Development of Mycobacterium abscessus subsp. massiliense Infection During Sirolimus Therapy

Among nontuberculous mycobacterial pulmonary diseases (NTM-PDs), Mycobacterium abscessus species pulmonary disease (MABS-PD) is one of the most severe and intractable infections. We herein report a 45-year-old woman with advanced lymphangioleiomyomatosis (LAM) who developed MABS-PD while undergoing sirolimus therapy. MABS-PD was immediately controlled using antibiotic therapy, although the patient's lung transplant registration was significantly delayed. To our knowledge, this is the first case report on the development of NTM-PD in a patient with LAM before lung transplantation. This case suggests that the early diagnosis and optimal treatment of NTM-PD are crucial in patients with advanced LAM.

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - year:2023

Enthalten in:

Internal medicine (Tokyo, Japan) - (2023) vom: 27. Nov.

Sprache:

Englisch

Beteiligte Personen:

Yanagisawa, Atsushi [VerfasserIn]
Takimoto, Takayuki [VerfasserIn]
Kurahara, Yu [VerfasserIn]
Tsuyuguchi, Kazunari [VerfasserIn]
Yoshida, Shiomi [VerfasserIn]
Hirose, Masaki [VerfasserIn]
Inoue, Yoshikazu [VerfasserIn]
Arai, Toru [VerfasserIn]

Links:

Volltext

Themen:

Journal Article
Lymphangioleiomyomatosis
Mycobacterium abscessus species
Nontuberculous mycobacterial pulmonary disease
Sirolimus

Anmerkungen:

Date Revised 26.11.2023

published: Print-Electronic

Citation Status Publisher

doi:

10.2169/internalmedicine.2847-23

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM364996617