Can single-inhaler Beclometasone Dipropionate/Formoterol Fumarate/Glycopyrronium therapy postpone or save biologics for severe asthma?

Copyright © 2023 Elsevier Ltd. All rights reserved..

Inhaled corticosteroids, along with beta2-agonists and anti-muscarinics, represent the cornerstone of asthma treatment. Although the advent of monoclonal antibodies has dramatically changed severe asthma management, there are still patients ineligible or with poor response to biologics. Moreover, high costs associated with monoclonal antibodies prescription are still an open issue, leading clinicians to carefully assess cost-benefit ratio before their administration. From this perspective, the use of single-inhaler Beclometasone Dipropionate/Formoterol Fumarate/Glycopyrronium in patients with severe asthma could not only improve their clinical and functional performance, but also postpone biologic prescription, with positive repercussions on healthcare costs.

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - volume:83

Enthalten in:

Pulmonary pharmacology & therapeutics - 83(2023) vom: 28. Dez., Seite 102270

Sprache:

Englisch

Beteiligte Personen:

Dragonieri, Silvano [VerfasserIn]
Quaranta, Vitaliano Nicola [VerfasserIn]
Portacci, Andrea [VerfasserIn]
Carpagnano, Giovanna Elisiana [VerfasserIn]

Links:

Volltext

Themen:

Anti-Asthmatic Agents
Antibodies, Monoclonal
Beclometasone Dipropionate
Beclomethasone
Biologic
Biological Products
Bronchodilator Agents
Drug Combinations
Formoterol Fumarate
Glycopyrrolate
Glycopyrronium
Inhaler
KGZ1SLC28Z
Letter
Severe asthma
V92SO9WP2I
W34SHF8J2K

Anmerkungen:

Date Completed 16.12.2023

Date Revised 16.12.2023

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1016/j.pupt.2023.102270

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM364996099