The characterization of CD8+ T-cell responses in COVID-19
This review gives an overview of the protective role of CD8+ T cells in SARS-CoV-2 infection. The cross-reactive responses intermediated by CD8+ T cells in unexposed cohorts are described. Additionally, the relevance of resident CD8+ T cells in the upper and lower airway during infection and CD8+ T-cell responses following vaccination are discussed, including recent worrisome breakthrough infections and variants of concerns (VOCs). Lastly, we explain the correlation between CD8+ T cells and COVID-19 severity. This review aids in a deeper comprehension of the association between CD8+ T cells and SARS-CoV-2 and broadens a vision for future exploration.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:13 |
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| Enthalten in: |
Emerging microbes & infections - 13(2024), 1 vom: 03. Jan., Seite 2287118 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Yang, Yuanting [VerfasserIn] |
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| Links: |
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| Themen: |
CD8-Positive T-Lymphocytes |
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| Anmerkungen: |
Date Completed 15.01.2024 Date Revised 15.01.2024 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1080/22221751.2023.2287118 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM364821892 |
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| 520 | |a This review gives an overview of the protective role of CD8+ T cells in SARS-CoV-2 infection. The cross-reactive responses intermediated by CD8+ T cells in unexposed cohorts are described. Additionally, the relevance of resident CD8+ T cells in the upper and lower airway during infection and CD8+ T-cell responses following vaccination are discussed, including recent worrisome breakthrough infections and variants of concerns (VOCs). Lastly, we explain the correlation between CD8+ T cells and COVID-19 severity. This review aids in a deeper comprehension of the association between CD8+ T cells and SARS-CoV-2 and broadens a vision for future exploration | ||
| 650 | 4 | |a Journal Article | |
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| 650 | 4 | |a SARS-CoV-2 | |
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| 700 | 1 | |a Miller, Heather |e verfasserin |4 aut | |
| 700 | 1 | |a Byazrova, Maria G |e verfasserin |4 aut | |
| 700 | 1 | |a Cndotti, Fabio |e verfasserin |4 aut | |
| 700 | 1 | |a Benlagha, Kamel |e verfasserin |4 aut | |
| 700 | 1 | |a Camara, Niels Olsen Saraiva |e verfasserin |4 aut | |
| 700 | 1 | |a Shi, Junming |e verfasserin |4 aut | |
| 700 | 1 | |a Forsman, Huamei |e verfasserin |4 aut | |
| 700 | 1 | |a Lee, Pamela |e verfasserin |4 aut | |
| 700 | 1 | |a Yang, Lu |e verfasserin |4 aut | |
| 700 | 1 | |a Filatov, Alexander |e verfasserin |4 aut | |
| 700 | 1 | |a Zhai, Zhimin |e verfasserin |4 aut | |
| 700 | 1 | |a Liu, Chaohong |e verfasserin |4 aut | |
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