Predictive performance of the sequential organ failure assessment score for in-hospital mortality in patients with end-stage kidney disease in intensive care units : A multicenter registry in Japan
© 2023 International Society for Apheresis and Japanese Society for Apheresis..
INTRODUCTION: There is limited evidence regarding whether the performance of the Sequential Organ Failure Assessment (SOFA) score differs between patients with and without end-stage kidney disease (ESKD) in intensive care units (ICUs).
METHODS: We used a multicenter registry (Japanese Intensive care Patient Database) to enroll adult ICU patients between April 2018 and March 2021. We recalibrated the SOFA score using a logistic regression model and evaluated its predictive ability in both ESKD and non-ESKD groups. The primary outcome was in-hospital mortality.
RESULTS: 128 134 patients were enrolled. The AUROC of the SOFA score was lower in the ESKD group than in the non-ESKD group [0.789 (95% CI, 0.774-0.804) vs. 0.846 (95% CI, 0.841-0.850)]. The calibration plot revealed good performance in both groups. However, it overestimated in-hospital mortality in ESKD groups.
CONCLUSION: The SOFA score demonstrated good predictive ability in patients with and without ESKD, but it overestimated the in-hospital mortality in ESKD patients.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:28 |
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| Enthalten in: |
Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy - 28(2024), 2 vom: 05. März, Seite 305-313 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Shimada, Hiroki [VerfasserIn] |
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| Links: |
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| Themen: |
Clinical prediction model |
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| Anmerkungen: |
Date Completed 05.03.2024 Date Revised 13.03.2024 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1111/1744-9987.14089 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM364763981 |
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| 100 | 1 | |a Shimada, Hiroki |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Predictive performance of the sequential organ failure assessment score for in-hospital mortality in patients with end-stage kidney disease in intensive care units |b A multicenter registry in Japan |
| 264 | 1 | |c 2024 | |
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| 500 | |a Date Completed 05.03.2024 | ||
| 500 | |a Date Revised 13.03.2024 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2023 International Society for Apheresis and Japanese Society for Apheresis. | ||
| 520 | |a INTRODUCTION: There is limited evidence regarding whether the performance of the Sequential Organ Failure Assessment (SOFA) score differs between patients with and without end-stage kidney disease (ESKD) in intensive care units (ICUs) | ||
| 520 | |a METHODS: We used a multicenter registry (Japanese Intensive care Patient Database) to enroll adult ICU patients between April 2018 and March 2021. We recalibrated the SOFA score using a logistic regression model and evaluated its predictive ability in both ESKD and non-ESKD groups. The primary outcome was in-hospital mortality | ||
| 520 | |a RESULTS: 128 134 patients were enrolled. The AUROC of the SOFA score was lower in the ESKD group than in the non-ESKD group [0.789 (95% CI, 0.774-0.804) vs. 0.846 (95% CI, 0.841-0.850)]. The calibration plot revealed good performance in both groups. However, it overestimated in-hospital mortality in ESKD groups | ||
| 520 | |a CONCLUSION: The SOFA score demonstrated good predictive ability in patients with and without ESKD, but it overestimated the in-hospital mortality in ESKD patients | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a clinical prediction model | |
| 650 | 4 | |a end-stage kidney disease | |
| 650 | 4 | |a in-hospital mortality | |
| 650 | 4 | |a intensive care unit | |
| 650 | 4 | |a sequential organ failure assessment score | |
| 700 | 1 | |a Matsuoka, Yoshinori |e verfasserin |4 aut | |
| 700 | 1 | |a Miyakoshi, Chisato |e verfasserin |4 aut | |
| 700 | 1 | |a Ito, Jiro |e verfasserin |4 aut | |
| 700 | 1 | |a Seo, Ryutaro |e verfasserin |4 aut | |
| 700 | 1 | |a Ariyoshi, Koichi |e verfasserin |4 aut | |
| 700 | 1 | |a Yamamoto, Yosuke |e verfasserin |4 aut | |
| 700 | 1 | |a Mima, Hiroyuki |e verfasserin |4 aut | |
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