Detailed high quality surface-based mouse CAD model suitable for electromagnetic simulations
© 2023 IOP Publishing Ltd..
Transcranial magnetic stimulation (TMS) studies with small animals can provide useful knowledge of activating regions and mechanisms. Along with this, functional magnetic resonance imaging (fMRI) in mice and rats is increasingly often used to draw important conclusions about brain connectivity and functionality. For cases of both low- and high-frequency TMS studies, a high-quality computational surface-based rodent model may be useful as a tool for performing supporting modeling and optimization tasks. This work presents the development and usage of an accurate CAD model of a mouse that has been optimized for use in computational electromagnetic modeling in any frequency range. It is based on the labeled atlas data of the Digimouse archive. The model includes a relatively accurate four-compartment brain representation (the 'whole brain' according to the original terminology, external cerebrum, cerebellum, and striatum [9]) and contains 21 distinct compartments in total. Four examples of low- and high frequency modeling have been considered to demonstrate the utility and applicability of the model.
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2023 |
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Erschienen: |
2023 |
Enthalten in: |
Zur Gesamtaufnahme - volume:10 |
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Enthalten in: |
Biomedical physics & engineering express - 10(2023), 1 vom: 30. Nov. |
Sprache: |
Englisch |
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Beteiligte Personen: |
Serano, Peter [VerfasserIn] |
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Links: |
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Themen: |
Animal CAD models |
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Anmerkungen: |
Date Completed 01.12.2023 Date Revised 13.01.2024 published: Electronic Citation Status MEDLINE |
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doi: |
10.1088/2057-1976/ad0e14 |
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funding: |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM364751533 |
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520 | |a Transcranial magnetic stimulation (TMS) studies with small animals can provide useful knowledge of activating regions and mechanisms. Along with this, functional magnetic resonance imaging (fMRI) in mice and rats is increasingly often used to draw important conclusions about brain connectivity and functionality. For cases of both low- and high-frequency TMS studies, a high-quality computational surface-based rodent model may be useful as a tool for performing supporting modeling and optimization tasks. This work presents the development and usage of an accurate CAD model of a mouse that has been optimized for use in computational electromagnetic modeling in any frequency range. It is based on the labeled atlas data of the Digimouse archive. The model includes a relatively accurate four-compartment brain representation (the 'whole brain' according to the original terminology, external cerebrum, cerebellum, and striatum [9]) and contains 21 distinct compartments in total. Four examples of low- and high frequency modeling have been considered to demonstrate the utility and applicability of the model | ||
650 | 4 | |a Journal Article | |
650 | 4 | |a Research Support, Non-U.S. Gov't | |
650 | 4 | |a MRI | |
650 | 4 | |a TMS | |
650 | 4 | |a animal CAD models | |
650 | 4 | |a electromagnetic modeling | |
650 | 4 | |a fMRI | |
650 | 4 | |a mouse brain connectomes | |
700 | 1 | |a Makaroff, Sergey |e verfasserin |4 aut | |
700 | 1 | |a Ackerman, Jerome L |e verfasserin |4 aut | |
700 | 1 | |a Nummenmaa, Aapo |e verfasserin |4 aut | |
700 | 1 | |a Noetscher, Gregory M |e verfasserin |4 aut | |
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