Early predictors of clinical deterioration in intermediate-high risk pulmonary embolism : clinical needs, research imperatives, and pathways forward
© The Author(s) 2023. Published by Oxford University Press on behalf of the European Society of Cardiology. All rights reserved. For permissions, please e-mail: journals.permissionsoup.com..
A subset of intermediate-high risk pulmonary embolism (PE) patients will suffer clinical deterioration in the early hours following the acute event. Current evidence-based guidelines for the management of acute PE have provided limited direction for identification of which intermediate-high risk PE patients will go on to develop haemodynamic decompensation. Furthermore, a paucity of data further hampers guideline recommendations regarding the optimal approach and duration of intensive monitoring, best methods to assess the early response to anticoagulation, and the ideal window for reperfusion therapy, if decompensation threatens. The aim of the present article is to identify the current unmet needs related to the early identification of intermediate-high risk PE patients at higher risk of clinical deterioration and mortality during the early hours after the acute cardiovascular event and suggest some potential strategies to further explore gaps in the literature.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:13 |
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| Enthalten in: |
European heart journal. Acute cardiovascular care - 13(2024), 3 vom: 11. März, Seite 297-303 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Zuin, Marco [VerfasserIn] |
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| Links: |
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| Themen: |
Clinical deterioration |
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| Anmerkungen: |
Date Completed 13.03.2024 Date Revised 13.03.2024 published: Print Citation Status MEDLINE |
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| doi: |
10.1093/ehjacc/zuad140 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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NLM36458923X |
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| 520 | |a © The Author(s) 2023. Published by Oxford University Press on behalf of the European Society of Cardiology. All rights reserved. For permissions, please e-mail: journals.permissionsoup.com. | ||
| 520 | |a A subset of intermediate-high risk pulmonary embolism (PE) patients will suffer clinical deterioration in the early hours following the acute event. Current evidence-based guidelines for the management of acute PE have provided limited direction for identification of which intermediate-high risk PE patients will go on to develop haemodynamic decompensation. Furthermore, a paucity of data further hampers guideline recommendations regarding the optimal approach and duration of intensive monitoring, best methods to assess the early response to anticoagulation, and the ideal window for reperfusion therapy, if decompensation threatens. The aim of the present article is to identify the current unmet needs related to the early identification of intermediate-high risk PE patients at higher risk of clinical deterioration and mortality during the early hours after the acute cardiovascular event and suggest some potential strategies to further explore gaps in the literature | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Clinical deterioration | |
| 650 | 4 | |a Intermediate-high risk | |
| 650 | 4 | |a Mortality | |
| 650 | 4 | |a Pulmonary embolism | |
| 650 | 4 | |a Risk stratification | |
| 650 | 4 | |a Thrombolysis | |
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| 700 | 1 | |a Piazza, Gregory |e verfasserin |4 aut | |
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