Coumarin-derived Hydroxamic Acids as Histone Deacetylase Inhibitors : A Review of Anti-cancer Activities

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Since coumarin and hydroxamic acid compounds are well-known in medicinal chemistry, a variety of their derivatives have been highlighted due to their potential uses for plentiful treatments. Different compounds of their derivatives acting through diverse activities, such as anti-tumor, anti-cancer, anti-inflammation, and histone deacetylase inhibition, have been comprehensively investigated by many researchers over the years. This present review provides the latest literature and knowledge on hydroxamic acids derived from coumarin. Overall, some recent advancements in biological activities of hybrid derivatives of hydroxamic acids containing coumarin moieties in medicinal chemistry are discussed.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:24

Enthalten in:

Anti-cancer agents in medicinal chemistry - 24(2024), 1 vom: 13., Seite 18-29

Sprache:

Englisch

Beteiligte Personen:

Khai, Nguyen Quang [VerfasserIn]
Vu, Tran Khac [VerfasserIn]

Links:

Volltext

Themen:

Activity
Anti-cancer activities.
Antineoplastic Agents
Biological
Coumarin
Coumarins
EC 3.5.1.98
Histone Deacetylase Inhibitors
Histone Deacetylases
Hybrids
Hydroxamic Acids
Journal Article
Review
Scaffold

Anmerkungen:

Date Completed 31.01.2024

Date Revised 21.02.2024

published: Print

Citation Status MEDLINE

doi:

10.2174/0118715206272112231102063919

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM364495073