Daytime hypoglycemic episodes during the use of an advanced hybrid closed loop system
Copyright © 2023. Published by Elsevier B.V..
AIMS: The use of advanced hybrid closed loop systems is spreading due to the beneficial effects on glycometabolic control obtained in patients with type 1 diabetes. However, hypoglycemic episodes can be sometimes a matter of concern. We aim to compare the hypoglycemic risk of an advanced hybrid closed loop system and a predictive low glucose suspend sensor augmented pump.
METHODS: In this retrospective three months observational study, we included 30 patients using Medtronic Minimed™ 780G advanced hybrid closed loop system and 30 patients using a Medtronic Minimed™ predictive low glucose suspend sensor augmented pump.
RESULTS: The advanced hybrid closed loop system reduced the time spent above 180 mg/dL threshold and increased the time in range as compared to the predictive low glucose suspend. No severe hypoglycemia occurred in both groups and no differences were observed in the percentage of time spent below 70 mg/dl and 54 mg/dl glucose threshold. Nevertheless, more hypoglycemic episodes were recorded during daytime, but not in nighttime, with the use of the advanced hybrid closed loop system.
CONCLUSIONS: Our results confirmed the general improvement of glycemic outcomes obtained with the advanced hybrid closed loop system; however more hypoglycemic episodes during daytime were evident.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2023 |
|---|---|
| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:206 |
|---|---|
| Enthalten in: |
Diabetes research and clinical practice - 206(2023) vom: 15. Dez., Seite 111011 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Rossi, Antonio [VerfasserIn] |
|---|
| Links: |
|---|
| Anmerkungen: |
Date Completed 16.12.2023 Date Revised 16.12.2023 published: Print-Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1016/j.diabres.2023.111011 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM364485868 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM364485868 | ||
| 003 | DE-627 | ||
| 005 | 20231227133212.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231226s2023 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.diabres.2023.111011 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1230.xml |
| 035 | |a (DE-627)NLM364485868 | ||
| 035 | |a (NLM)37956944 | ||
| 035 | |a (PII)S0168-8227(23)00774-X | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Rossi, Antonio |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Daytime hypoglycemic episodes during the use of an advanced hybrid closed loop system |
| 264 | 1 | |c 2023 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 16.12.2023 | ||
| 500 | |a Date Revised 16.12.2023 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2023. Published by Elsevier B.V. | ||
| 520 | |a AIMS: The use of advanced hybrid closed loop systems is spreading due to the beneficial effects on glycometabolic control obtained in patients with type 1 diabetes. However, hypoglycemic episodes can be sometimes a matter of concern. We aim to compare the hypoglycemic risk of an advanced hybrid closed loop system and a predictive low glucose suspend sensor augmented pump | ||
| 520 | |a METHODS: In this retrospective three months observational study, we included 30 patients using Medtronic Minimed™ 780G advanced hybrid closed loop system and 30 patients using a Medtronic Minimed™ predictive low glucose suspend sensor augmented pump | ||
| 520 | |a RESULTS: The advanced hybrid closed loop system reduced the time spent above 180 mg/dL threshold and increased the time in range as compared to the predictive low glucose suspend. No severe hypoglycemia occurred in both groups and no differences were observed in the percentage of time spent below 70 mg/dl and 54 mg/dl glucose threshold. Nevertheless, more hypoglycemic episodes were recorded during daytime, but not in nighttime, with the use of the advanced hybrid closed loop system | ||
| 520 | |a CONCLUSIONS: Our results confirmed the general improvement of glycemic outcomes obtained with the advanced hybrid closed loop system; however more hypoglycemic episodes during daytime were evident | ||
| 650 | 4 | |a Observational Study | |
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Advanced hybrid closed loop system | |
| 650 | 4 | |a Daytime hypoglycemia | |
| 650 | 4 | |a Hypoglycemia | |
| 650 | 4 | |a Nighttime hypoglycemia | |
| 650 | 4 | |a Type 1 diabetes | |
| 650 | 7 | |a Blood Glucose |2 NLM | |
| 650 | 7 | |a Insulin |2 NLM | |
| 650 | 7 | |a Hypoglycemic Agents |2 NLM | |
| 650 | 7 | |a Glucose |2 NLM | |
| 650 | 7 | |a IY9XDZ35W2 |2 NLM | |
| 700 | 1 | |a Montefusco, Laura |e verfasserin |4 aut | |
| 700 | 1 | |a Reseghetti, Elia |e verfasserin |4 aut | |
| 700 | 1 | |a Pastore, Ida Fabrizia |e verfasserin |4 aut | |
| 700 | 1 | |a Rossi, Giada |e verfasserin |4 aut | |
| 700 | 1 | |a Usuelli, Vera |e verfasserin |4 aut | |
| 700 | 1 | |a Loretelli, Cristian |e verfasserin |4 aut | |
| 700 | 1 | |a Boci, Denisa |e verfasserin |4 aut | |
| 700 | 1 | |a Ben Nasr, Moufida |e verfasserin |4 aut | |
| 700 | 1 | |a D'Addio, Francesca |e verfasserin |4 aut | |
| 700 | 1 | |a Bucciarelli, Loredana |e verfasserin |4 aut | |
| 700 | 1 | |a Argenti, Sabrina |e verfasserin |4 aut | |
| 700 | 1 | |a Morpurgo, Paola |e verfasserin |4 aut | |
| 700 | 1 | |a Lunati, Maria Elena |e verfasserin |4 aut | |
| 700 | 1 | |a Fiorina, Paolo |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Diabetes research and clinical practice |d 1993 |g 206(2023) vom: 15. Dez., Seite 111011 |w (DE-627)NLM01260335X |x 1872-8227 |7 nnns |
| 773 | 1 | 8 | |g volume:206 |g year:2023 |g day:15 |g month:12 |g pages:111011 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1016/j.diabres.2023.111011 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 206 |j 2023 |b 15 |c 12 |h 111011 | ||