Test-retest repeatability and agreement of the quantitative contrast sensitivity function test : towards the validation of a new clinical endpoint

© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature..

PURPOSE: The purpose of this study is to investigate test-retest reliability and agreement of the quantitative contrast sensitivity function test (qCSF) in the retina clinic.

METHODS: A total of 121 right eyes of 121 patients were tested and consecutively re-tested with qCSF in the retina clinic. Outcomes included area under the logarithm of contrast sensitivity function curve (AULCSF), contrast acuity, and contrast sensitivity thresholds at 1-18 cycles per degree (cpd). Test-retest means were compared with paired t-test, variability was compared with the Brown-Forsythe test, and intraclass correlation coefficient (ICC) and Bland Altman plots evaluated reliability and agreement.

RESULTS: Mean test-retest differences for all qCSF metrics ranged from 0.02 to 0.05 log units without statistically significant differences in variability. Standard deviations ranged from 0.08 to 0.14. Coefficients of repeatability ranged from 0.16 to 0.27 log units. ICC > 0.9 for all metrics except 1cpd (ICC = 0.84, all p < 0.001); AULCSF ICC = 0.971.

CONCLUSION: qCSF-measured contrast sensitivity shows great test-retest repeatability and agreement in the retina clinic.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:262

Enthalten in:

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie - 262(2024), 3 vom: 01. März, Seite 813-822

Sprache:

Englisch

Beteiligte Personen:

Finn, Matthew [VerfasserIn]
Vingopoulos, Filippos [VerfasserIn]
Zhao, Yan [VerfasserIn]
Zhou, Paul [VerfasserIn]
Bannerman, Augustine [VerfasserIn]
Romano, Francesco [VerfasserIn]
Ding, Xinyi [VerfasserIn]
Hassan, Zakariyya [VerfasserIn]
Patel, Nimesh A [VerfasserIn]
Wu, David M [VerfasserIn]
Miller, John B [VerfasserIn]

Links:

Volltext

Themen:

Agreement
Clinical endpoints
Contrast sensitivity
Functional vision
Journal Article
Quantitative contrast sensitivity function
Repeatability
Retina
Validation
Visual function

Anmerkungen:

Date Completed 04.03.2024

Date Revised 04.03.2024

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1007/s00417-023-06291-y

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM364473568