Evaluation of resistance risk in soil due to antibiotics during application of penicillin V fermentation residue
The soil application of hydrothermally treated penicillin V fermentation residue (PFR) is attractive but challenged, due to the concern of the resistance risk in soil related to residual antibiotics. In this study, a lab-scale incubation experiment was conducted to investigate the influence of penicillin V on antibiotic resistance genes (ARGs) in PFR-amended soil via qPCR. The introduced penicillin V in soil could not be persistent, and its degradation occurred mainly within 2 days. The higher number of soil ARGs was detected under 108 mg/kg of penicillin V than lower contents (≤54 mg/kg). Additionally, the relative abundance of ARGs was higher in soil spiked with penicillin V than that in blank soil, and the great increase in the relative abundance of soil ARGs occurred earlier under 108 mg/kg of penicillin V than lower contents. The horizontal gene transfer might contribute to the shift of ARGs in PFR-amended soil. The results indicated that the residual penicillin V could cause the proliferation of soil ARGs and should be completely removed by hydrothermal treatment before soil application. The results of this study provide a comprehensive understanding of the resistance risk posed by penicillin V during the application of hydrothermally pretreated PFR.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - year:2023 |
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| Enthalten in: |
Environmental technology - (2023) vom: 13. Nov., Seite 1-9 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Gong, Picheng [VerfasserIn] |
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| Links: |
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| Themen: |
Antibiotic resistance gene |
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| Anmerkungen: |
Date Revised 23.11.2023 published: Print-Electronic Citation Status Publisher |
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| doi: |
10.1080/09593330.2023.2283807 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM364469129 |
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| 520 | |a The soil application of hydrothermally treated penicillin V fermentation residue (PFR) is attractive but challenged, due to the concern of the resistance risk in soil related to residual antibiotics. In this study, a lab-scale incubation experiment was conducted to investigate the influence of penicillin V on antibiotic resistance genes (ARGs) in PFR-amended soil via qPCR. The introduced penicillin V in soil could not be persistent, and its degradation occurred mainly within 2 days. The higher number of soil ARGs was detected under 108 mg/kg of penicillin V than lower contents (≤54 mg/kg). Additionally, the relative abundance of ARGs was higher in soil spiked with penicillin V than that in blank soil, and the great increase in the relative abundance of soil ARGs occurred earlier under 108 mg/kg of penicillin V than lower contents. The horizontal gene transfer might contribute to the shift of ARGs in PFR-amended soil. The results indicated that the residual penicillin V could cause the proliferation of soil ARGs and should be completely removed by hydrothermal treatment before soil application. The results of this study provide a comprehensive understanding of the resistance risk posed by penicillin V during the application of hydrothermally pretreated PFR | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Antibiotic resistance gene | |
| 650 | 4 | |a fermentation residue | |
| 650 | 4 | |a hydrothermal treatment | |
| 650 | 4 | |a penicillin V | |
| 650 | 4 | |a soil application | |
| 700 | 1 | |a Liu, Huiling |e verfasserin |4 aut | |
| 700 | 1 | |a Yu, Tingting |e verfasserin |4 aut | |
| 700 | 1 | |a Jiang, Cuishuang |e verfasserin |4 aut | |
| 700 | 1 | |a Gou, Enfang |e verfasserin |4 aut | |
| 700 | 1 | |a Guan, Jingze |e verfasserin |4 aut | |
| 700 | 1 | |a Chen, Huayuan |e verfasserin |4 aut | |
| 700 | 1 | |a Kang, Haoze |e verfasserin |4 aut | |
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