Systematic Review of Outcomes for Assessment of Medication Adherence Enhancing Interventions : An ISPOR Special Interest Group Report

Copyright © 2023 International Society for Pharmacoeconomics and Outcomes Research, Inc. Published by Elsevier Inc. All rights reserved..

OBJECTIVES: The lack of universal guidance on outcome measures for evaluating medication adherence enhancing interventions (MAEIs) poses a challenge for assessing their effectiveness. This literature review aimed to provide a systematic overview of outcome measures currently used for the value assessment of MAEIs.

METHODS: We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines and searched MEDLINE, PsycINFO, Scopus, CINAHL, and Academic Search Complete for randomized and nonrandomized clinical trials, prospective cohort studies, model-based economic evaluations, and value frameworks published in English between January 2010 and September 2020. Two independent reviewers screened all titles and abstracts, followed by a full-text review. Due to the large number of relevant studies, data extraction was limited to articles published between January 2018 and September 2020. We collected data on the general characteristics of the study, the type of intervention, and the outcomes measured.

RESULTS: We screened 14 685 records and identified 308 articles for data extraction. Behavioral interventions were the most common (n = 143), followed by educational interventions (n = 110) and mixed-method interventions (n = 73). Outcomes were clustered into 7 categories with medication adherence (n = 286) being the most frequently measured, followed by clinical outcomes (n = 155), health-related quality of life (n = 57), resource use (n = 43), patient satisfaction (n = 31), economic outcomes (n = 18), and other outcomes (n = 76).

CONCLUSIONS: Various outcomes measures have been used to evaluate MAEIs, with only a small number of studies exploring economic and patient-reported outcomes. Future research is warranted to develop a consensus-based set of criteria for assessing MAEIs to facilitate the comparison of interventions and enable informed decision making.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:27

Enthalten in:

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research - 27(2024), 2 vom: 01. Feb., Seite 133-142

Sprache:

Englisch

Beteiligte Personen:

Ágh, Tamás [VerfasserIn]
Hiligsmann, Mickaël [VerfasserIn]
Borah, Bijan [VerfasserIn]
Beaudart, Charlotte [VerfasserIn]
Turcu-Stiolica, Adina [VerfasserIn]
Manias, Elizabeth [VerfasserIn]
Jakab, Ivett [VerfasserIn]
Pednekar, Priti [VerfasserIn]
Zeber, John [VerfasserIn]
Peterson, Andrew M [VerfasserIn]

Links:

Volltext

Themen:

Journal Article
Medication adherence
Medication adherence enhancing intervention
Outcome measure
Systematic Review
Systematic literature review
Value assessment

Anmerkungen:

Date Completed 23.01.2024

Date Revised 25.04.2024

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1016/j.jval.2023.10.016

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM364444959