Mechanical ventilation practices in Asian intensive care units : A multicenter cross-sectional study
Copyright © 2023 Elsevier Inc. All rights reserved..
PURPOSE: This study investigated current practices of mechanical ventilation in Asian intensive care units, focusing on tidal volume, plateau pressure, and positive end-expiratory pressure (PEEP).
MATERIALS AND METHODS: In this multicenter cross-sectional study, data on mechanical ventilation and clinical outcomes were collected. Predictors of mortality were analyzed by univariate and multivariable logistic regression. A scoring system was generated to predict 28-day mortality.
RESULTS: A total of 1408 patients were enrolled. In 138 patients with acute respiratory distress syndrome (ARDS), 65.9% were on a tidal volume ≤ 8 ml/kg predicted body weight (PBW), and 71.3% were on sufficient PEEP. In 1270 patients without ARDS, 88.8% were on a tidal volume ≤ 10 ml/kg PBW. A plateau pressure < 30 cmH2O was measured in 92.2% of patients. Mortality rates increased from 13% to 74% as the generated predictive score increased from 5 to ≥8.5. Income classification, age, SOFA score, PaO2/FiO2 ratio, plateau pressure, number of vasopressors, and steroid use were associated with mortality.
CONCLUSIONS: In Asia, low tidal volume ventilation and sufficient PEEP were underused in patients with ARDS. The majority of patients without ARDS were on intermediate tidal volumes. Country income, age, and severity of illness were associated with mortality.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:79 |
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| Enthalten in: |
Journal of critical care - 79(2024) vom: 01. Feb., Seite 154452 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Nam, Kyung Hun [VerfasserIn] |
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| Links: |
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| Themen: |
Asia |
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| Anmerkungen: |
Date Completed 16.12.2023 Date Revised 18.03.2024 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.jcrc.2023.154452 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM364406089 |
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| 100 | 1 | |a Nam, Kyung Hun |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Mechanical ventilation practices in Asian intensive care units |b A multicenter cross-sectional study |
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| 500 | |a Date Revised 18.03.2024 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2023 Elsevier Inc. All rights reserved. | ||
| 520 | |a PURPOSE: This study investigated current practices of mechanical ventilation in Asian intensive care units, focusing on tidal volume, plateau pressure, and positive end-expiratory pressure (PEEP) | ||
| 520 | |a MATERIALS AND METHODS: In this multicenter cross-sectional study, data on mechanical ventilation and clinical outcomes were collected. Predictors of mortality were analyzed by univariate and multivariable logistic regression. A scoring system was generated to predict 28-day mortality | ||
| 520 | |a RESULTS: A total of 1408 patients were enrolled. In 138 patients with acute respiratory distress syndrome (ARDS), 65.9% were on a tidal volume ≤ 8 ml/kg predicted body weight (PBW), and 71.3% were on sufficient PEEP. In 1270 patients without ARDS, 88.8% were on a tidal volume ≤ 10 ml/kg PBW. A plateau pressure < 30 cmH2O was measured in 92.2% of patients. Mortality rates increased from 13% to 74% as the generated predictive score increased from 5 to ≥8.5. Income classification, age, SOFA score, PaO2/FiO2 ratio, plateau pressure, number of vasopressors, and steroid use were associated with mortality | ||
| 520 | |a CONCLUSIONS: In Asia, low tidal volume ventilation and sufficient PEEP were underused in patients with ARDS. The majority of patients without ARDS were on intermediate tidal volumes. Country income, age, and severity of illness were associated with mortality | ||
| 650 | 4 | |a Multicenter Study | |
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Asia | |
| 650 | 4 | |a Low tidal volumes | |
| 650 | 4 | |a Lung-protective ventilation | |
| 650 | 4 | |a Mechanical ventilation | |
| 700 | 1 | |a Phua, Jason |e verfasserin |4 aut | |
| 700 | 1 | |a Du, Bin |e verfasserin |4 aut | |
| 700 | 1 | |a Ohshimo, Shinichiro |e verfasserin |4 aut | |
| 700 | 1 | |a Kim, Hwa Jung |e verfasserin |4 aut | |
| 700 | 1 | |a Lim, Chae-Man |e verfasserin |4 aut | |
| 700 | 1 | |a Myatra, Sheila Nainan |e verfasserin |4 aut | |
| 700 | 1 | |a Adib, Nik Azman Bin Nik |e verfasserin |4 aut | |
| 700 | 1 | |a Arabi, Yaseen M |e verfasserin |4 aut | |
| 700 | 1 | |a Chan, Ming-Cheng |e verfasserin |4 aut | |
| 700 | 1 | |a Faruq, Mohammad Omar |e verfasserin |4 aut | |
| 700 | 1 | |a Redjeki, Ike Sri |e verfasserin |4 aut | |
| 700 | 1 | |a Son, Do Ngoc |e verfasserin |4 aut | |
| 700 | 1 | |a Nafees, Khalid Mahmood Khan |e verfasserin |4 aut | |
| 700 | 1 | |a Priyankara, Dilshan |e verfasserin |4 aut | |
| 700 | 1 | |a Patjanasoontorn, Boonsong |e verfasserin |4 aut | |
| 700 | 1 | |a Palo, Jose Emmanuel |e verfasserin |4 aut | |
| 700 | 1 | |a Konkayev, Aidos |e verfasserin |4 aut | |
| 700 | 1 | |a Shrestha, Gentle Sunder |e verfasserin |4 aut | |
| 700 | 1 | |a Koh, Younsuck |e verfasserin |4 aut | |
| 700 | 0 | |a IMPROVE Study Investigators, for the Asian Critical Care Clinical Trials Group |e verfasserin |4 aut | |
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