Fitostimoline® in fibro-endoscopic and trans-nasal trans-speculum septoplasty as a beneficial tool to improve post-surgical outcome : Preliminary results of a case-control study
Copyright © 2023 The Authors. Published by Elsevier Inc. All rights reserved..
OBJECTIVES: Topic treatment can be useful to improve short and long-term nasal outcomes after nasal surgery, reducing discomfort and risk of synechia. This study aimed at evaluating the effect on clinical outcomes of nasal packaging using Fitostimoline® gauze in FESS and septoplasty.
METHODS: A case-control study on hospitalized patients was performed in a tertiary referral center. The control group included 20 patients treated with the standard surgical protocol for septoplasty and standard nasal packaging; treatment group included 21 patients underwent same surgical procedure but in whom the nasal tampon was wrapped with a gauze containing Fitostimoline® before being placed into the nose.
RESULTS: Patients in treatment group had better outcomes than control; nasal mucosa showed better healing - recovery of normal color- in those patients in whom we applied the Fitostimoline® gauze around tampons. Moreover, 100 % patients in the treatment group did not refer discomfort during at tampon removal versus 60 % subjects in the control group who referred pain, tension or tearing during the same action.
CONCLUSION: Our results, although preliminary because of the small cohort of subjects included, suggest that the apposition of a gauze with Fitostimoline® after nasal surgery might improve the mucosal healing with consequent reduction of patients discomfort during the post-surgical period.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2024 2023 |
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| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:45 |
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| Enthalten in: |
American journal of otolaryngology - 45(2023), 1 vom: 21. Jan., Seite 104107 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
De Luca, Pietro [VerfasserIn] |
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| Links: |
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| Themen: |
FEES |
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| Anmerkungen: |
Date Completed 16.12.2023 Date Revised 16.12.2023 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.amjoto.2023.104107 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM364404876 |
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| 245 | 1 | 0 | |a Fitostimoline® in fibro-endoscopic and trans-nasal trans-speculum septoplasty as a beneficial tool to improve post-surgical outcome |b Preliminary results of a case-control study |
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| 500 | |a Date Revised 16.12.2023 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2023 The Authors. Published by Elsevier Inc. All rights reserved. | ||
| 520 | |a OBJECTIVES: Topic treatment can be useful to improve short and long-term nasal outcomes after nasal surgery, reducing discomfort and risk of synechia. This study aimed at evaluating the effect on clinical outcomes of nasal packaging using Fitostimoline® gauze in FESS and septoplasty | ||
| 520 | |a METHODS: A case-control study on hospitalized patients was performed in a tertiary referral center. The control group included 20 patients treated with the standard surgical protocol for septoplasty and standard nasal packaging; treatment group included 21 patients underwent same surgical procedure but in whom the nasal tampon was wrapped with a gauze containing Fitostimoline® before being placed into the nose | ||
| 520 | |a RESULTS: Patients in treatment group had better outcomes than control; nasal mucosa showed better healing - recovery of normal color- in those patients in whom we applied the Fitostimoline® gauze around tampons. Moreover, 100 % patients in the treatment group did not refer discomfort during at tampon removal versus 60 % subjects in the control group who referred pain, tension or tearing during the same action | ||
| 520 | |a CONCLUSION: Our results, although preliminary because of the small cohort of subjects included, suggest that the apposition of a gauze with Fitostimoline® after nasal surgery might improve the mucosal healing with consequent reduction of patients discomfort during the post-surgical period | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a FEES | |
| 650 | 4 | |a Gauze | |
| 650 | 4 | |a Nasal breathing | |
| 650 | 4 | |a Nasal mucosa | |
| 650 | 4 | |a Ointment | |
| 650 | 4 | |a Septoplasty | |
| 650 | 4 | |a Surgical outcomes | |
| 650 | 4 | |a Synechia | |
| 700 | 1 | |a La Mantia, Ignazio |e verfasserin |4 aut | |
| 700 | 1 | |a Gioacchini, Federico Maria |e verfasserin |4 aut | |
| 700 | 1 | |a Re, Massimo |e verfasserin |4 aut | |
| 700 | 1 | |a Radici, Marco |e verfasserin |4 aut | |
| 700 | 1 | |a Camaioni, Angelo |e verfasserin |4 aut | |
| 700 | 1 | |a Di Stadio, Arianna |e verfasserin |4 aut | |
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