Development and validation of an analytical methodology based on solvent extraction and gas chromatography for determining pesticides in royal jelly and propolis
Copyright © 2023 Elsevier Ltd. All rights reserved..
We propose a new analytical methodology to determine seven pesticides (atrazine, chlorpyrifos, chlorfenvinphos, α-endosulfan, bromopropylate, coumaphos, and τ-fluvalinate) in royal jelly and propolis products using gas chromatography-mass spectrometry. Sample treatment, with minor modifications for propolis, consisted of a solvent extraction with a hexane and isopropanol mixture, and a further clean-up step. Meanwhile, chromatographic analysis (<25 min) was performed in a DB-5MS column under programmed temperature conditions. In all cases we validated the method in terms of selectivity, limits of detection (0.1-2.8 μg kg-1) and quantification (0.3-9.2 μg kg-1), linearity, matrix effect (<±20 %), trueness (recoveries between 93 % and 118 %), and precision (relative standard deviation < 11 %). All royal jelly liquid dietary supplements were positive for chlorfenvinphos and, in the case of one of them, for α-endosulfan; chlorfenvinphos was determined in some fresh royal jelly samples, and no pesticide residues were detected in the propolis samples analysed.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2024 2023 |
|---|---|
| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:437 |
|---|---|
| Enthalten in: |
Food chemistry - 437(2023), Pt 2 vom: 30. März, Seite 137911 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Fuente-Ballesteros, Adrián [VerfasserIn] |
|---|
| Links: |
|---|
| Anmerkungen: |
Date Completed 22.11.2023 Date Revised 22.11.2023 published: Print-Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1016/j.foodchem.2023.137911 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM36440468X |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM36440468X | ||
| 003 | DE-627 | ||
| 005 | 20231226095349.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231226s2024 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.foodchem.2023.137911 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1214.xml |
| 035 | |a (DE-627)NLM36440468X | ||
| 035 | |a (NLM)37948804 | ||
| 035 | |a (PII)S0308-8146(23)02529-3 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Fuente-Ballesteros, Adrián |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Development and validation of an analytical methodology based on solvent extraction and gas chromatography for determining pesticides in royal jelly and propolis |
| 264 | 1 | |c 2024 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 22.11.2023 | ||
| 500 | |a Date Revised 22.11.2023 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2023 Elsevier Ltd. All rights reserved. | ||
| 520 | |a We propose a new analytical methodology to determine seven pesticides (atrazine, chlorpyrifos, chlorfenvinphos, α-endosulfan, bromopropylate, coumaphos, and τ-fluvalinate) in royal jelly and propolis products using gas chromatography-mass spectrometry. Sample treatment, with minor modifications for propolis, consisted of a solvent extraction with a hexane and isopropanol mixture, and a further clean-up step. Meanwhile, chromatographic analysis (<25 min) was performed in a DB-5MS column under programmed temperature conditions. In all cases we validated the method in terms of selectivity, limits of detection (0.1-2.8 μg kg-1) and quantification (0.3-9.2 μg kg-1), linearity, matrix effect (<±20 %), trueness (recoveries between 93 % and 118 %), and precision (relative standard deviation < 11 %). All royal jelly liquid dietary supplements were positive for chlorfenvinphos and, in the case of one of them, for α-endosulfan; chlorfenvinphos was determined in some fresh royal jelly samples, and no pesticide residues were detected in the propolis samples analysed | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Food analysis | |
| 650 | 4 | |a Food safety | |
| 650 | 4 | |a Gas chromatography-mass spectrometry | |
| 650 | 4 | |a Method validation | |
| 650 | 4 | |a Pesticides | |
| 650 | 4 | |a Propolis | |
| 650 | 4 | |a Royal jelly | |
| 650 | 4 | |a Sample treatment | |
| 650 | 7 | |a Pesticides |2 NLM | |
| 650 | 7 | |a royal jelly |2 NLM | |
| 650 | 7 | |a L497I37F0C |2 NLM | |
| 650 | 7 | |a Propolis |2 NLM | |
| 650 | 7 | |a 9009-62-5 |2 NLM | |
| 650 | 7 | |a Chlorfenvinphos |2 NLM | |
| 650 | 7 | |a F2G9XS1W91 |2 NLM | |
| 650 | 7 | |a Endosulfan |2 NLM | |
| 650 | 7 | |a OKA6A6ZD4K |2 NLM | |
| 650 | 7 | |a Solvents |2 NLM | |
| 700 | 1 | |a Jano, Ana |e verfasserin |4 aut | |
| 700 | 1 | |a Bernal, José |e verfasserin |4 aut | |
| 700 | 1 | |a Ares, Ana M |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Food chemistry |d 1995 |g 437(2023), Pt 2 vom: 30. März, Seite 137911 |w (DE-627)NLM076785823 |x 1873-7072 |7 nnns |
| 773 | 1 | 8 | |g volume:437 |g year:2023 |g number:Pt 2 |g day:30 |g month:03 |g pages:137911 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1016/j.foodchem.2023.137911 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 437 |j 2023 |e Pt 2 |b 30 |c 03 |h 137911 | ||