Frequency and Risk Factors for Persistent and Concomitant Symptoms after Hospital Discharge for Coronavirus Disease 2019 in the Pre-omicron Period : An Exploratory Longitudinal Study
Copyright © Japan Medical Association..
Introduction: Many countries have reported persistent and concomitant symptoms of coronavirus disease 2019 (COVID-19). This study aimed to identify persistent COVID-19 and concomitant symptoms in discharged patients and identify the risk factors for such symptoms.
Methods: This study enrolled patients with COVID-19 who were admitted to the University of Fukui Hospital, Japan, and discharged between April 3, 2020, and August 19, 2021. Persistent and concomitant symptoms were confirmed based on medical examinations approximately 2 weeks after discharge. Patient characteristics and symptoms were collected from the patients' medical records by a technical assistant.
Results: This study included 120 patients (60 men and 60 women; mean age, 53.5 ± 17.0 years). Persistent COVID-19 symptoms were observed in 62 patients (51.7%). The most common persistent symptom was weakened physical function, manifesting as physical weakness (48.4%) and muscle weakness (29.0%). Binary logistic regression analysis revealed that cough with expectoration within the acute phase of COVID-19 was a risk factor predisposing patients to COVID-19 sequelae (odds ratio: 2.94, 95% confidence interval: 1.300 - 6.630, p = 0.009).
Conclusions: The study findings suggest that productive cough in the acute phase is associated with subsequent physical and muscle weaknesses in the subacute phase.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:6 |
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| Enthalten in: |
JMA journal - 6(2023), 4 vom: 16. Okt., Seite 437-447 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Kobuchi, Taketsune [VerfasserIn] |
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| Links: |
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| Themen: |
Coronavirus disease of 2019 |
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| Anmerkungen: |
Date Revised 10.11.2023 published: Print-Electronic Citation Status PubMed-not-MEDLINE |
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| doi: |
10.31662/jmaj.2023-0054 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM364334304 |
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| 245 | 1 | 0 | |a Frequency and Risk Factors for Persistent and Concomitant Symptoms after Hospital Discharge for Coronavirus Disease 2019 in the Pre-omicron Period |b An Exploratory Longitudinal Study |
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| 500 | |a Date Revised 10.11.2023 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status PubMed-not-MEDLINE | ||
| 520 | |a Copyright © Japan Medical Association. | ||
| 520 | |a Introduction: Many countries have reported persistent and concomitant symptoms of coronavirus disease 2019 (COVID-19). This study aimed to identify persistent COVID-19 and concomitant symptoms in discharged patients and identify the risk factors for such symptoms | ||
| 520 | |a Methods: This study enrolled patients with COVID-19 who were admitted to the University of Fukui Hospital, Japan, and discharged between April 3, 2020, and August 19, 2021. Persistent and concomitant symptoms were confirmed based on medical examinations approximately 2 weeks after discharge. Patient characteristics and symptoms were collected from the patients' medical records by a technical assistant | ||
| 520 | |a Results: This study included 120 patients (60 men and 60 women; mean age, 53.5 ± 17.0 years). Persistent COVID-19 symptoms were observed in 62 patients (51.7%). The most common persistent symptom was weakened physical function, manifesting as physical weakness (48.4%) and muscle weakness (29.0%). Binary logistic regression analysis revealed that cough with expectoration within the acute phase of COVID-19 was a risk factor predisposing patients to COVID-19 sequelae (odds ratio: 2.94, 95% confidence interval: 1.300 - 6.630, p = 0.009) | ||
| 520 | |a Conclusions: The study findings suggest that productive cough in the acute phase is associated with subsequent physical and muscle weaknesses in the subacute phase | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Coronavirus disease of 2019 | |
| 650 | 4 | |a Cough | |
| 650 | 4 | |a Fatigue | |
| 650 | 4 | |a Japan | |
| 650 | 4 | |a Logistic Models | |
| 650 | 4 | |a Muscle Weakness | |
| 650 | 4 | |a Patient Discharge | |
| 650 | 4 | |a Risk Factors | |
| 700 | 1 | |a Onishi, Hidenori |e verfasserin |4 aut | |
| 700 | 1 | |a Yamamura, Osamu |e verfasserin |4 aut | |
| 700 | 1 | |a Sakamaki, Ippei |e verfasserin |4 aut | |
| 700 | 1 | |a Iwasaki, Hiromichi |e verfasserin |4 aut | |
| 700 | 1 | |a Hayashi, Hiroyuki |e verfasserin |4 aut | |
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