Muscle strength, not muscle mass, determines the health-related quality of life in Indonesian women with systemic lupus erythematosus
© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ..
OBJECTIVE: No study evaluated the impact of low muscle strength and mass on the Sarcopenia-related Quality of Life (SarQoL) in women with SLE.
METHODS: This cross-sectional study recruited 145 women with SLE consecutively; muscle strength was measured with a calibrated Jamar handheld dynamometer, muscle mass was measured with appendicular muscle mass index (Tanita MC-780 MAP body impedance analyser) and health-related quality of life with SarQoL Questionnaire. The cut-off points for low muscle strength, low muscle mass and sarcopenia were derived from the Asian Working Group on Sarcopenia 2019. Statistical analysis was conducted with a t-test for mean difference, and logistic regression was used to evaluate for low muscle strength contributing factors.
RESULTS: There was a significant difference in the mean total score of SarQoL in individuals with normal compared with low muscle strength (74.36 vs 64.85; mean difference 9.50; 95% CI 2.10 to 5.33; p<0.001). On the other hand, there was no difference in individuals with normal compared with low muscle mass (71.07 vs 70.79; mean difference 0.28; -5.18 to 5.74; p=0.91). After minimally adjusted with age, we found moderate-severe joint pain (B -9.280; p<0.001) and low muscle strength (B -6.979; p=0.001) to be independently associated with low mean SarQoL total score.
CONCLUSION: There was a lower total SarQoL score in individuals with low muscle strength but not with low muscle mass.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:10 |
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| Enthalten in: |
Lupus science & medicine - 10(2023), 2 vom: 07. Nov. |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Sumantri, Stevent [VerfasserIn] |
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| Links: |
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| Themen: |
Journal Article |
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| Anmerkungen: |
Date Completed 06.11.2023 Date Revised 12.12.2023 published: Print Citation Status MEDLINE |
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| doi: |
10.1136/lupus-2023-001025 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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NLM364108266 |
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| 245 | 1 | 0 | |a Muscle strength, not muscle mass, determines the health-related quality of life in Indonesian women with systemic lupus erythematosus |
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| 500 | |a Date Revised 12.12.2023 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. | ||
| 520 | |a OBJECTIVE: No study evaluated the impact of low muscle strength and mass on the Sarcopenia-related Quality of Life (SarQoL) in women with SLE | ||
| 520 | |a METHODS: This cross-sectional study recruited 145 women with SLE consecutively; muscle strength was measured with a calibrated Jamar handheld dynamometer, muscle mass was measured with appendicular muscle mass index (Tanita MC-780 MAP body impedance analyser) and health-related quality of life with SarQoL Questionnaire. The cut-off points for low muscle strength, low muscle mass and sarcopenia were derived from the Asian Working Group on Sarcopenia 2019. Statistical analysis was conducted with a t-test for mean difference, and logistic regression was used to evaluate for low muscle strength contributing factors | ||
| 520 | |a RESULTS: There was a significant difference in the mean total score of SarQoL in individuals with normal compared with low muscle strength (74.36 vs 64.85; mean difference 9.50; 95% CI 2.10 to 5.33; p<0.001). On the other hand, there was no difference in individuals with normal compared with low muscle mass (71.07 vs 70.79; mean difference 0.28; -5.18 to 5.74; p=0.91). After minimally adjusted with age, we found moderate-severe joint pain (B -9.280; p<0.001) and low muscle strength (B -6.979; p=0.001) to be independently associated with low mean SarQoL total score | ||
| 520 | |a CONCLUSION: There was a lower total SarQoL score in individuals with low muscle strength but not with low muscle mass | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Outcome Assessment, Health Care | |
| 650 | 4 | |a Quality of LIfe | |
| 650 | 4 | |a Risk Factors | |
| 650 | 4 | |a Systemic Lupus Erythematosus | |
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| 700 | 1 | |a Rengganis, Iris |e verfasserin |4 aut | |
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