Behavioural outcomes of children born with intrauterine growth restriction : protocol for a systematic review and meta-analysis

© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ..

INTRODUCTION: Intrauterine growth restriction (IUGR) is a pregnancy condition, which is associated with poor perinatal outcomes and long-term neurodevelopmental impairment. Several studies also investigated the impact of IUGR on child behaviour (eg, internalising and externalising behaviour, social competencies). However, so far, no systematic review or meta-analysis has been conducted that summarises these effects while considering relevant third variables such as type of IUGR diagnosis and control group, or concurrent cognitive abilities. The objective of this study is to summarise the current evidence regarding the relationship between IUGR and behavioural outcomes from early childhood to young adulthood. Additionally, to explore how third variables such as type of control group, or cognitive abilities, relate to this association.

METHODS: Search strategy: The following electronic databases will be searched-Web of Science, Medline Ovid, PsycInfo, Cochrane Library, Scopus and Embase.

INCLUSION CRITERIA: observational (eg, cohort studies and case-control studies) and intervention studies (if standard care is used and norm values are reported for the control group) will be included if they quantitatively compare children with and without IUGR from the age of 2 to 18 years. The main outcomes are internalising and externalising behaviour, and social competencies.

ETHICS AND DISSEMINATION: No ethics approval was necessary for this protocol. Dissemination of findings will be done by publishing the results in peer-reviewed journals. The results of this systematic review will provide guidance for practice and counselling for clinicians and therapists facing patients affected by IUGR and their families.

PROSPERO REGISTRATION NUMBER: CRD42022347467.

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - volume:13

Enthalten in:

BMJ open - 13(2023), 11 vom: 01. Nov., Seite e074417

Sprache:

Englisch

Beteiligte Personen:

Yakoub, Ninib [VerfasserIn]
Reinelt, Tilman [VerfasserIn]
Natalucci, Giancarlo [VerfasserIn]

Links:

Volltext

Themen:

Adolescent
Child & adolescent psychiatry
Developmental neurology & neurodisability
Journal Article
PAEDIATRICS
Paediatric intensive & critical care
Prenatal diagnosis
Research Support, Non-U.S. Gov't

Anmerkungen:

Date Completed 03.11.2023

Date Revised 08.11.2023

published: Electronic

Citation Status MEDLINE

doi:

10.1136/bmjopen-2023-074417

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM364061960