Bilateral intracochlear schwannomas : histopathological confirmation and outcomes following tumour removal and cochlear implantation with lateral wall electrodes
© 2023. The Author(s)..
Intracochlear schwannomas (ICS) are very rare benign tumours of the inner ear. We present histopathological proof of the extremely rare bilateral occurrence of intracochlear schwannomas with negative blood genetic testing for neurofibromatosis type 2 (NF2). Bilateral schwannomas are typically associated with the condition NF2 and this case is presumed to have either mosaicism for NF2 or sporadic development of bilateral tumours. For progressive bilateral tumour growth and associated profound hearing loss, surgical intervention via partial cochleoectomy, tumour removal, preservation of the modiolus, and simultaneous cochlear implantation with lateral wall electrode carrier with basal double electrode contacts was performed. The right side was operated on first with a 14-month gap between each side. The hearing in aided speech recognition for consonant-nucleus-consonant (CNC) phonemes in quiet improved from 57% to 83% 12 months after bilateral cochlear implantation (CI). Bilateral intracochlear schwannomas in non-NF2 patients are extremely rare but should be considered in cases of progressive bilateral hearing loss. Successful tumour removal and cochlear implantation utilizing a lateral wall electrode is possible and can achieve good hearing outcomes.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:71 |
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| Enthalten in: |
HNO - 71(2023), 12 vom: 30. Dez., Seite 802-808 |
| Sprache: |
Englisch |
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| Weiterer Titel: |
Bilaterale intracochleäre Schwannome: histopathologische Bestätigung und Ergebnisse nach Tumorentfernung und Cochleaimplantation mit „lateral wall“-Elektroden |
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| Beteiligte Personen: |
Quick, Mark E [VerfasserIn] |
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| Links: |
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| Themen: |
Acoustic neuroma |
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| Anmerkungen: |
Date Completed 23.11.2023 Date Revised 24.11.2023 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1007/s00106-023-01379-7 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM363960031 |
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| 245 | 1 | 0 | |a Bilateral intracochlear schwannomas |b histopathological confirmation and outcomes following tumour removal and cochlear implantation with lateral wall electrodes |
| 246 | 3 | 3 | |a Bilaterale intracochleäre Schwannome: histopathologische Bestätigung und Ergebnisse nach Tumorentfernung und Cochleaimplantation mit „lateral wall“-Elektroden |
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| 520 | |a © 2023. The Author(s). | ||
| 520 | |a Intracochlear schwannomas (ICS) are very rare benign tumours of the inner ear. We present histopathological proof of the extremely rare bilateral occurrence of intracochlear schwannomas with negative blood genetic testing for neurofibromatosis type 2 (NF2). Bilateral schwannomas are typically associated with the condition NF2 and this case is presumed to have either mosaicism for NF2 or sporadic development of bilateral tumours. For progressive bilateral tumour growth and associated profound hearing loss, surgical intervention via partial cochleoectomy, tumour removal, preservation of the modiolus, and simultaneous cochlear implantation with lateral wall electrode carrier with basal double electrode contacts was performed. The right side was operated on first with a 14-month gap between each side. The hearing in aided speech recognition for consonant-nucleus-consonant (CNC) phonemes in quiet improved from 57% to 83% 12 months after bilateral cochlear implantation (CI). Bilateral intracochlear schwannomas in non-NF2 patients are extremely rare but should be considered in cases of progressive bilateral hearing loss. Successful tumour removal and cochlear implantation utilizing a lateral wall electrode is possible and can achieve good hearing outcomes | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Acoustic neuroma | |
| 650 | 4 | |a Cochlea | |
| 650 | 4 | |a Cochlear implant | |
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| 650 | 4 | |a Intralabyrinthine | |
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| 700 | 1 | |a Chester-Browne, Ronel |e verfasserin |4 aut | |
| 700 | 1 | |a Kuthubutheen, Jafri |e verfasserin |4 aut | |
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