How do Mutations of Mycobacterium Genes Cause Drug Resistance in Tuberculosis?

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A steady increase in the prevalence of drug-resistant tuberculosis (DR-TB) has already been reported in Pakistan. In addition, DR-TB is gradually changing from one-drug resistance to multi-drug resistance, which is a serious challenge for tuberculosis treatment. This review provides an overview of the anti-tuberculosis drugs and focuses on the molecular mechanisms of drug resistance in Mycobacterium tuberculosis, with the hope that it will contribute to the study of drug resistance in response to the emergence of multidrug-resistant tuberculosis.

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - year:2023

Enthalten in:

Current pharmaceutical biotechnology - (2023) vom: 06. Okt.

Sprache:

Englisch

Beteiligte Personen:

Hou, Kaiying [VerfasserIn]
Jabeen, Riffat [VerfasserIn]
Sun, Lin [VerfasserIn]
Wei, Jianshe [VerfasserIn]

Links:

Volltext

Themen:

Journal Article
Tuberculosis; Anti-tuberculosis drugs; Drug-resistant tuberculosis; Mycobacterium tuberculosis; Molecular mechanism; gene mutatioTuberculosis; Anti-tuberculosis drugs; Drug-resistant tuberculosis; Mycobacterium tuberculosis; Molecular mechanism; gene mutation

Anmerkungen:

Date Revised 27.10.2023

published: Print-Electronic

Citation Status Publisher

doi:

10.2174/0113892010257816230920053547

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM363808809