The predictive value of liver tests for the presence of liver metastases
© 2023 The Authors..
Aim: To analyze the predictive value of biochemical liver tests in patients with malignant melanoma, breast, colorectal or lung cancers at the time of diagnosis of liver metastases.
Methods: A retrospective review of patients with the above-mentioned solid tumors at MedStar Georgetown University Hospital from 2016-2020.
Results: The highest optimal cutoff according to sensitivity and specificity for the presence of liver metastases was for AST ≥1.5 × ULN for melanoma, lung, and breast cancers and ≥2 × ULN for colorectal cancer, ALT ≥1.25 × ULN for melanoma, breast and colorectal cancers and ≥1.5 × ULN for lung cancer, and ALP ≥1.5 × ULN for melanoma, breast and colorectal cancers.
Conclusion: Using thresholds of liver enzymes above the ULN may improve the diagnostic accuracy for the presence of liver metastases.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:10 |
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| Enthalten in: |
Hepatic oncology - 10(2023), 3 vom: 23. Sept., Seite HEP48 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Kimchy, Alexandra V [VerfasserIn] |
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| Links: |
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| Themen: |
Breast neoplasms |
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| Anmerkungen: |
Date Revised 28.10.2023 published: Electronic-eCollection Citation Status PubMed-not-MEDLINE |
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| doi: |
10.2217/hep-2023-0003 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM363776761 |
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| 100 | 1 | |a Kimchy, Alexandra V |e verfasserin |4 aut | |
| 245 | 1 | 4 | |a The predictive value of liver tests for the presence of liver metastases |
| 264 | 1 | |c 2023 | |
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| 500 | |a Date Revised 28.10.2023 | ||
| 500 | |a published: Electronic-eCollection | ||
| 500 | |a Citation Status PubMed-not-MEDLINE | ||
| 520 | |a © 2023 The Authors. | ||
| 520 | |a Aim: To analyze the predictive value of biochemical liver tests in patients with malignant melanoma, breast, colorectal or lung cancers at the time of diagnosis of liver metastases | ||
| 520 | |a Methods: A retrospective review of patients with the above-mentioned solid tumors at MedStar Georgetown University Hospital from 2016-2020 | ||
| 520 | |a Results: The highest optimal cutoff according to sensitivity and specificity for the presence of liver metastases was for AST ≥1.5 × ULN for melanoma, lung, and breast cancers and ≥2 × ULN for colorectal cancer, ALT ≥1.25 × ULN for melanoma, breast and colorectal cancers and ≥1.5 × ULN for lung cancer, and ALP ≥1.5 × ULN for melanoma, breast and colorectal cancers | ||
| 520 | |a Conclusion: Using thresholds of liver enzymes above the ULN may improve the diagnostic accuracy for the presence of liver metastases | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a breast neoplasms | |
| 650 | 4 | |a colonic neoplasms | |
| 650 | 4 | |a liver biochemical tests | |
| 650 | 4 | |a liver metastases | |
| 650 | 4 | |a lung neoplasms | |
| 650 | 4 | |a malignant melanoma | |
| 700 | 1 | |a Singh, Harjit |e verfasserin |4 aut | |
| 700 | 1 | |a Parikh, Esha |e verfasserin |4 aut | |
| 700 | 1 | |a Rosenberg, Jessica |e verfasserin |4 aut | |
| 700 | 1 | |a Sanghavi, Kavya |e verfasserin |4 aut | |
| 700 | 1 | |a Lewis, James H |e verfasserin |4 aut | |
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