The Current Mismatch Between COVID-19 Clinical Trial Design and the Evolving Profile of Hospitalized Patients : A Retrospective Cohort Analysis

© The Author(s) 2023. Published by Oxford University Press on behalf of Infectious Diseases Society of America. All rights reserved. For permissions, please e-mail: journals.permissionsoup.com..

Evaluating 100 adult coronavirus disease 2019 (COVID-19) patients at a Madrid hospital, we identified a mismatch between current clinical trial designs and the evolving profile of hospitalized patients. Most patients were ineligible due to design constraints, suggesting a need to rethink trial criteria for a more accurate representation of the hospitalized COVID-19 cohort.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:78

Enthalten in:

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 78(2024), 4 vom: 10. Apr., Seite 918-921

Sprache:

Englisch

Beteiligte Personen:

Montejano, Rocio [VerfasserIn]
Soler-Carracedo, Alfredo [VerfasserIn]
Borobia, Alberto M [VerfasserIn]
Martin-Quiros, Alejandro [VerfasserIn]
Grandioso, David [VerfasserIn]
Cañada, Carlos [VerfasserIn]
Roman, Alicia [VerfasserIn]
Arribas, Jose R [VerfasserIn]

Links:

Volltext

Themen:

COVID-19
Clinical trial
Hospitalized patients
Journal Article
Patient Eligibility
Retrospective Analysis

Anmerkungen:

Date Completed 12.04.2024

Date Revised 12.04.2024

published: Print

Citation Status MEDLINE

doi:

10.1093/cid/ciad655

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM363747370