Comprehensive Long-Term Outcomes Following Mandibular Distraction Osteogenesis
OBJECTIVE: To describe long-term outcomes and complications following mandibular distraction osteogenesis (MDO) in a diverse patient cohort.
DESIGN: Cross-sectional study.
SETTING: Single tertiary-care pediatric center.
PATIENTS: Forty-eight patients previously undergoing MDO with minimum 4-year follow-up.
MAIN OUTCOME MEASURES: Respiratory outcomes, feeding patterns, dental development, motor/sensory nerve function, temporo-mandibular joint function, and postsurgical scarring.
RESULTS: Forty-six patients with a median age of 7 years were evaluated. Of 20 nonsyndromic patients, none required additional airway procedures, none required continuous positive airway pressure (CPAP) during sleep, and 19 (95%) fed exclusively by mouth. Among 26 syndromic patients, 7 (27%) required CPAP and 8 (31%) were tube fed. Permanent first molar differences were seen in the majority of subjects; patterns of damage interfering with function were more common in syndromic (13/28, 46%) compared to nonsyndromic (5/24, 21%; P = .014) subjects. MDO prior to age two was associated with more frequent and worse dental damage (P = .001). Inferior alveolar nerve and marginal mandibular nerve function were fully intact in 37 (80%) and 39 (85%) of patients, respectively. Three patients (6%), all with associated genetic syndromes, demonstrated severe nerve impairment. By the Vancouver scar scale, ≥ 80% of surgical scars were rated in the most favorable category for each quality assessed. Temporomandibular joint dysfunction was rare.
CONCLUSIONS: MDO shows highly favorable long-term respiratory, feeding, nerve, and scar outcomes in nonsyndromic patients, although permanent molar changes not precluding tooth viability are commonly seen. Patients with associated syndromes demonstrate respiratory and feeding benefits, but higher rates of dental and nerve abnormalities.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - year:2023 |
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| Enthalten in: |
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association - (2023) vom: 17. Okt., Seite 10556656231206884 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Kosyk, Mychajlo S [VerfasserIn] |
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| Links: |
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| Themen: |
Distraction osteogenesis |
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| Anmerkungen: |
Date Revised 18.10.2023 published: Print-Electronic Citation Status Publisher |
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| doi: |
10.1177/10556656231206884 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM363418318 |
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| 500 | |a Date Revised 18.10.2023 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status Publisher | ||
| 520 | |a OBJECTIVE: To describe long-term outcomes and complications following mandibular distraction osteogenesis (MDO) in a diverse patient cohort | ||
| 520 | |a DESIGN: Cross-sectional study | ||
| 520 | |a SETTING: Single tertiary-care pediatric center | ||
| 520 | |a PATIENTS: Forty-eight patients previously undergoing MDO with minimum 4-year follow-up | ||
| 520 | |a MAIN OUTCOME MEASURES: Respiratory outcomes, feeding patterns, dental development, motor/sensory nerve function, temporo-mandibular joint function, and postsurgical scarring | ||
| 520 | |a RESULTS: Forty-six patients with a median age of 7 years were evaluated. Of 20 nonsyndromic patients, none required additional airway procedures, none required continuous positive airway pressure (CPAP) during sleep, and 19 (95%) fed exclusively by mouth. Among 26 syndromic patients, 7 (27%) required CPAP and 8 (31%) were tube fed. Permanent first molar differences were seen in the majority of subjects; patterns of damage interfering with function were more common in syndromic (13/28, 46%) compared to nonsyndromic (5/24, 21%; P = .014) subjects. MDO prior to age two was associated with more frequent and worse dental damage (P = .001). Inferior alveolar nerve and marginal mandibular nerve function were fully intact in 37 (80%) and 39 (85%) of patients, respectively. Three patients (6%), all with associated genetic syndromes, demonstrated severe nerve impairment. By the Vancouver scar scale, ≥ 80% of surgical scars were rated in the most favorable category for each quality assessed. Temporomandibular joint dysfunction was rare | ||
| 520 | |a CONCLUSIONS: MDO shows highly favorable long-term respiratory, feeding, nerve, and scar outcomes in nonsyndromic patients, although permanent molar changes not precluding tooth viability are commonly seen. Patients with associated syndromes demonstrate respiratory and feeding benefits, but higher rates of dental and nerve abnormalities | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a distraction osteogenesis | |
| 650 | 4 | |a mandibular micrognathia | |
| 650 | 4 | |a nerve injuries | |
| 650 | 4 | |a scarring | |
| 650 | 4 | |a tooth abnormalities | |
| 700 | 1 | |a Salinero, Lauren K |e verfasserin |4 aut | |
| 700 | 1 | |a Morales, Carrie Z |e verfasserin |4 aut | |
| 700 | 1 | |a Shakir, Sameer |e verfasserin |4 aut | |
| 700 | 1 | |a Cielo, Christopher M |e verfasserin |4 aut | |
| 700 | 1 | |a Scott, Michelle |e verfasserin |4 aut | |
| 700 | 1 | |a Nah, Hyun-Duck |e verfasserin |4 aut | |
| 700 | 1 | |a Bartlett, Scott P |e verfasserin |4 aut | |
| 700 | 1 | |a Taylor, Jesse A |e verfasserin |4 aut | |
| 700 | 1 | |a Swanson, Jordan W |e verfasserin |4 aut | |
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