Systemic Therapy for Small-Cell Lung Cancer : ASCO-Ontario Health (Cancer Care Ontario) Guideline
PURPOSE: To provide evidence-based recommendations to practicing clinicians on the management of patients with small-cell lung cancer.
METHODS: An Expert Panel of medical oncology, thoracic surgery, radiation oncology, pulmonary, community oncology, research methodology, and advocacy experts were convened to conduct a literature search, which included systematic reviews, meta-analyses, and randomized controlled trials published from 1990 through 2022. Outcomes of interest included response rates, overall survival, disease-free survival or recurrence-free survival, and quality of life. Expert Panel members used available evidence and informal consensus to develop evidence-based guideline recommendations.
RESULTS: The literature search identified 95 relevant studies to inform the evidence base for this guideline.
RECOMMENDATIONS: Evidence-based recommendations were developed to address systemic therapy options, timing of therapy, treatment in patients who are older or with poor performance status, role of biomarkers, and use of myeloid-supporting agents in patients with small-cell lung cancer.Additional information is available at www.asco.org/thoracic-cancer-guidelines.
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2023 |
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Erschienen: |
2023 |
Enthalten in: |
Zur Gesamtaufnahme - volume:41 |
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Enthalten in: |
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 41(2023), 35 vom: 10. Dez., Seite 5448-5472 |
Sprache: |
Englisch |
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Beteiligte Personen: |
Khurshid, Humera [VerfasserIn] |
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Links: |
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Themen: |
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Anmerkungen: |
Date Completed 04.01.2024 Date Revised 04.01.2024 published: Print-Electronic Citation Status MEDLINE |
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doi: |
10.1200/JCO.23.01435 |
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funding: |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM363133739 |
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520 | |a PURPOSE: To provide evidence-based recommendations to practicing clinicians on the management of patients with small-cell lung cancer | ||
520 | |a METHODS: An Expert Panel of medical oncology, thoracic surgery, radiation oncology, pulmonary, community oncology, research methodology, and advocacy experts were convened to conduct a literature search, which included systematic reviews, meta-analyses, and randomized controlled trials published from 1990 through 2022. Outcomes of interest included response rates, overall survival, disease-free survival or recurrence-free survival, and quality of life. Expert Panel members used available evidence and informal consensus to develop evidence-based guideline recommendations | ||
520 | |a RESULTS: The literature search identified 95 relevant studies to inform the evidence base for this guideline | ||
520 | |a RECOMMENDATIONS: Evidence-based recommendations were developed to address systemic therapy options, timing of therapy, treatment in patients who are older or with poor performance status, role of biomarkers, and use of myeloid-supporting agents in patients with small-cell lung cancer.Additional information is available at www.asco.org/thoracic-cancer-guidelines | ||
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