Systemic Therapy for Small-Cell Lung Cancer : ASCO-Ontario Health (Cancer Care Ontario) Guideline

PURPOSE: To provide evidence-based recommendations to practicing clinicians on the management of patients with small-cell lung cancer.

METHODS: An Expert Panel of medical oncology, thoracic surgery, radiation oncology, pulmonary, community oncology, research methodology, and advocacy experts were convened to conduct a literature search, which included systematic reviews, meta-analyses, and randomized controlled trials published from 1990 through 2022. Outcomes of interest included response rates, overall survival, disease-free survival or recurrence-free survival, and quality of life. Expert Panel members used available evidence and informal consensus to develop evidence-based guideline recommendations.

RESULTS: The literature search identified 95 relevant studies to inform the evidence base for this guideline.

RECOMMENDATIONS: Evidence-based recommendations were developed to address systemic therapy options, timing of therapy, treatment in patients who are older or with poor performance status, role of biomarkers, and use of myeloid-supporting agents in patients with small-cell lung cancer.Additional information is available at www.asco.org/thoracic-cancer-guidelines.

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - volume:41

Enthalten in:

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 41(2023), 35 vom: 10. Dez., Seite 5448-5472

Sprache:

Englisch

Beteiligte Personen:

Khurshid, Humera [VerfasserIn]
Ismaila, Nofisat [VerfasserIn]
Bian, Jessica [VerfasserIn]
Dabney, Raetasha [VerfasserIn]
Das, Millie [VerfasserIn]
Ellis, Peter [VerfasserIn]
Feldman, Jill [VerfasserIn]
Hann, Christine [VerfasserIn]
Kulkarni, Swati [VerfasserIn]
Laskin, Janessa [VerfasserIn]
Manochakian, Rami [VerfasserIn]
Mishra, Deebya Raj [VerfasserIn]
Preeshagul, Isabel [VerfasserIn]
Reddy, Pavan [VerfasserIn]
Saxena, Ashish [VerfasserIn]
Weinberg, Frank [VerfasserIn]
Kalemkerian, Gregory P [VerfasserIn]

Links:

Volltext

Themen:

Journal Article
Practice Guideline

Anmerkungen:

Date Completed 04.01.2024

Date Revised 04.01.2024

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1200/JCO.23.01435

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM363133739