The Potential of Cannabidiol for Acute Respiratory Distress Syndrome in COVID-19

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COVID-19 disease manifests itself in a wide range of signs and symptoms, beginning with mild symptoms, such as fever, cough, and dyspnea, progressing to acute respiratory distress syndrome (ARDS) and death in some cases. The cytokine storm, or an excess of cytokines released locally, is assumed to be the primary cause of ARDS and mortality in COVID-19 patients. To enhance the survival rate of COVID-19 patients, early management of the cytokine storm with immunomodulators is crucial. Although the effectiveness of some immunosuppressants, such as corticosteroids and tocilizumab, has been studied in clinical trials, the administration of these drugs should be exercised cautiously. Cannabidiol (CBD) is a non-psychotropic phytocannabinoid from Cannabis sativa extracts with anti-inflammatory properties. This review is intended to discuss the possible utility of CBD for the management of COVID-19 patients, particularly those with ARDS.

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - volume:29

Enthalten in:

Current pharmaceutical design - 29(2023), 29 vom: 08., Seite 2291-2296

Sprache:

Englisch

Beteiligte Personen:

Azimi, Saeid [VerfasserIn]
Saghafi, Fatemeh [VerfasserIn]
Mohammadi, Mohammad Hossein [VerfasserIn]
Moghimi, Mohammad Hossein [VerfasserIn]
Akhavan, Seyed Ali [VerfasserIn]
Khataminia, Masoud [VerfasserIn]
Shirvani, Maria [VerfasserIn]
Sohrevardi, Seyed Mojtaba [VerfasserIn]
Jamialahmadi, Tannaz [VerfasserIn]
Sahebnasagh, Adeleh [VerfasserIn]
Sahebkar, Amirhossein [VerfasserIn]

Links:

Volltext

Themen:

19GBJ60SN5
Acute respiratory distress syndrome
COVID-19
Cannabidiol
Cannabidiol.
Cytokine
Cytokines
Immunosuppressant
Journal Article
Review
Survival rate

Anmerkungen:

Date Completed 27.11.2023

Date Revised 08.04.2024

published: Print

Citation Status MEDLINE

doi:

10.2174/0113816128275803230920094909

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM363116834